Therapeutic Confirmatory (Phase III)

3,259 trials 1,319 recruiting

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A study to investigate efficacy and safety with pegtibatinase compared to placebo in participants ≥12 to ≤65 years of age with classical hom… Pending

2023-504135-40-00 Classical Homocystinuria
Elranatamab Post Trial Access Study for Participants With Multiple Myeloma Pending

2023-505200-33-00 Multiple myeloma
Evaluation of the efficacy and safety of stiripentol in patients 6 years and older with primary hyperoxaluria type 1, 2 or 3 - CRYSTAL Pending

2023-508062-15-00 Primary Hyperoxaluria (PH) of all subtypes (PH1, PH2 an
IntReALL BCP 2020 – International Study for Treatment of Childhood Relapsed Precursor B-cell ALL 2020 Pending

2023-509392-17-00 Relapsed Acute Lymphoblastic Leukemia (ALL)
SEMAFORCRANIO : Multicenter, double-blind, parallel, randomized controlled trial of the efficacy of semaglutide in hypothalamic obesity seco… Pending

2024-511114-20-00 Craniopharyngioma
TIC-TAC-SAM « Comparison of two strategies of etoposide initiation in severe sporadic hemophagocytic lymphohistiocytosis in intensive care: … Pending

2024-511807-41-01 Hemophagocytic lymphohistiocytosis (HLH)
Feasibility of the Application of a new Six-month Treatment for multidrug-resistant tuberculosis (MDR-TB) patients in France (FAST-MDR) Pending

2024-512763-32-00 Patients diagnosed at the study sites with rifampicinre
A prospective, open-label, randomized, multicenter phase-III trial to evaluate the efficacy of pirtobrutinib and epcoritamab compared with R… Pending

2024-513445-37-00 previously untreated RT, irrespective of risk factors a
The Effect of Mitapivat on Cerebral Perfusion and Oxygen Metabolism in Sickle Cell Disease Pending

2024-513528-41-02 Sickle cell anaemia
Extension Study of ACT-EARLY Pending

2024-513676-18-00 Transthyretin Amyloidosis
MInimal residual Disease Adapted Strategy / IFM 2020-02 Pending

2024-513889-19-00 Multiple Myeloma
CANDISHORT : A randomized study of a short duration therapy for candidemia Pending

2024-514244-81-00 Uncomplicated candidemia
A Randomized Double-Blind, Placebo Controlled Trial of Abatacept (CTLA4-Ig) in Giant Cell Arteritis (ABAGART) Pending

2024-515287-31-00 Giant Cell Arteritis
A Clinical Trial to Investigate the Efficacy, Safety and Pharmacokinetics of Elsunersen in Children Pending

2024-515598-82-00 Voltage-gated sodium channel type II alpha subunit (SCN
Severe Erythema Multiforme - CORTICO Pending

2024-516018-39-00 Erythema multiforme (EM) in its severe form managed at
Rituximab therapy in anti-MAG patients with characteristics of good responders: THERAMAG study Pending

2024-516335-27-00 anti-MAG neuropathy
Tandem therapy LutaPol/ltraPol ( I 77Lu / 90Y-DOTATATE) as an effective method in the treatment of neuroendocrine neoplasmas. Pending

2024-516503-17-01 Diagnosed and histopathologically confirmed diffuse or
Open label safety study of tasimelteon indicated in the treatment of blind individuals with no light perception having problems synchronizin… Pending

2024-516721-31-00 Non-24 Hour Sleep-Wake Disorder
Comparison of neurocognitive outcome in two standard regimen for treatment of low-risk medulloblastoma (COGNITO-MB) Pending

2024-517133-40-00 newly diagnosed, non-metastatic, SHH-activated, TP53-wt
Prospective multicenter clinical trial for risk estimation and treatment stratification in low and intermediate risk neuroblastoma patients … Pending

2024-517295-37-00 low and intermediate risk neuroblastoma
RESET-TRD; a Randomised trial on oral ESketamine compared to Electroconvulsive Therapy for patients with Treatment Resistant Depression Pending

2024-517485-42-00 Non-psychotic therapy resistant unipolar depression
ASPIRIN - Acetylsalicylic acid versus placebo in addition to a local non-steroidal anti-inflammatory drug in the treatment of thrombotic epi… Pending

2024-517595-38-00 Thrombotic episodes in superficial venous malformations
IMpAct of CardiolRxTM oVer 6 months following IL-1 Blocker cessation in pERICarditis patients – MAVERIC: A randomized, double-blind, placebo… Pending

2024-517688-21-00 Recurrent Pericarditis
BALLAD Belgium - A trial to evaluate the potential benefit of adjuvant chemotherapy for small bowel adenocarcinoma. The Belgian component of… Pending

2024-518349-85-01 small bowel adenocarcinoma