Therapeutic Confirmatory (Phase III)

3,259 trials 1,319 recruiting

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Research study to look at how well the drug concizumab works in your body if you have haemophilia with inhibitors Ended

2023-506832-33-00 haemophilia A (HA) with inhibitors and haemophilia B (H 2019-11-06
A phase III multi-center, randomized, open-label study to evaluate the efficacy and safety of Lutathera in combination with best supportive … Ended

2023-507443-10-00 Patients with somatostatin receptor positive, well-diff 2019-11-04
Efficacy Study of Nivolumab Compared to Placebo in Prevention of Recurrence of Melanoma After Complete Resection of Stage IIB/C Melanoma (Ch… Ended

2022-502354-14-00 Completely resected Stage IIb/c melanoma 2019-10-28
Palbociclib for HR positive Isolated Local or Regional Recurrence of Breast Cancer Ended

2024-510776-20-00 Female or male patients with histologically confirmed H 2019-10-25
Respiratory effect of the LISA (Less Invasive surfactant administration) method with sedation by propofol versus absence of sedation: Double… Ended

2024-518836-36-00 Respiratory Distress Syndrome of preterm babies born < 2019-10-07
A Phase 3 Study Comparing Lenalidomide and Daratumumab Subcutaneous Injection (R-Dara SC) vs Lenalidomide and Dexamethasone (Rd) in Frail Su… Ended

2024-514088-25-00 Multiple Myeloma 2019-10-07
This is a randomized, double-blind, controlled trial to evaluate the efficacy and safety of cabozantinib in combination with nivolumab and i… Ended

2024-515616-47-00 Metastatic Renal Cell Carcinoma 2019-10-03
A Phase 3 clinical study to investigate the effects of BAN2401 in patients with Early Alzheimer's Disease. Ended

2024-510887-22-00 Mild cognitive impairment due to Alzheimer's disease or 2019-09-30
A Phase 3, Randomized, Double-blind Study of Chemotherapy plus Nivolumab versus Chemotherapy plus Placebo provided before surgery, followed … Ended

2022-502658-15-00 Resectable Stage II-IIIB Non-small cell lung cancer 2019-09-22
A Study to Evaluate the Efficacy and Safety of Ocrelizumab in Adults with Primary Progressive Multiple Sclerosis Ended

2023-505980-36-00 Primary progressive multiple sclerosis (PPMS) 2019-09-19
Trial assessing a regorafenib-irinotecan combination (REGIRI) versus regorafenib alone in metastatic colorectal cancer patients after failur… Ended

2024-512555-21-00 Metastatic colorectal cancer 2019-09-18
Study to compare the efficacy and safety of NT 201 (botulinum toxin) with placebo for the treatment of lower limb spasticity caused by strok… Ended

2023-505810-12-00 Lower limb spasticity 2019-09-03
Randomized Phase III Study of Standard Intensive Chemotherapy versus Intensive Chemotherapy with CPX-351 in Adult Patients with Newly Diagno… Ended

2023-503670-21-00 Patients with newly diagnosed AML and intermediate- or 2019-08-28
Study for patients with Primary Hyperoxaluria to evaluate the Long-Term Safety and Efficacy of DCR-PHXC Solution for Injection Ended

2024-512260-54-00 Primary Hyperoxaluria 2019-08-20
An open label, multicenter extension study in patients previously enrolled in a Genentch and/or F. Hoffmann-La Roche Ltd sponsored atezolizu… Ended

2023-506184-34-00 Advanced Malignancies 2019-08-09
A Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 (Peginterferon beta-1a) in Pediatric Participants for the Treatment of… Ended

2023-505624-56-00 Relapsing Remitting Multiple Sclerosis (RRMS) 2019-08-07
Durvalumab or Placebo in Combination With Gemcitabine/Cisplatin in Patients With 1st Line Advanced Biliary Tract Cancer (TOPAZ-1) Ended

2023-507405-34-00 First-line patients with advanced biliary tract cancers 2019-08-07
Comparison of Carboplatin and Cisplatin in patients with extracranial malignant germ cell tumours Ended

2023-507582-25-00 Malignant Extracranial Germ Cell Tumours (MGCT) 2019-08-02
A phase 3B, open-label, single-arm, rollover study to evaluate long-term safety of Luspatercept in subjects who have participated in other L… Ended

2022-502498-40-00 myelodysplastic syndrome (MDS); beta (β)-thalassemia (T 2019-07-26
Phase III randomized trial of atezolizumab in elderly patients with advanced Non-Small-Cell Lung Cancer and receiving monthly carboplatin wi… Ended

2024-515946-17-00 Non Small Cell Lung Cancer 2019-07-22
Efficacy and Safety of Erenumab in Pediatric Subjects with Episodic Migraine Ended

2023-504930-23-00 Episodic Migraine 2019-07-19
A study of androgen deprivation therapy (ADT) plus apalutamide in patients with prostate cancer Ended

2023-506153-38-00 High-risk localized or locally advanced prostate cancer 2019-07-11
Randomized double blind double dummy control trial comparing the safety and efficacy of rituximab versus oral cyclophosphamide in severe for… Ended

2024-514885-38-00 severe forms of mucous membrane pemphigoid 2019-07-11
A phase III randomized trial evaluating chemotherapy followed by pelvic reirradiation versus chemotherapy alone as pre-operative treatment f… Ended

2024-514705-62-00 Recurrent rectal cancer after local excision 2019-07-08