Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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Radiotherapy to enhance the effects of an immune therapy before tumor surgery in patients with advanced non-small cell lung cancer (NSCLC). … Ended

2023-504536-18-00 Resectable, locally advanced non-small cell lung cancer 2024-07-31
Phase 2 Study of Adjuvant V940 and Pembrolizumab in Renal Cell Carcinoma Ended

2023-505177-32-00 Intermediate-high -risk RCC, high-risk RCC who have und 2024-07-31
A phase 2 study to investigate the efficacy and safety of CYP‑001 in combination with corticosteroids in adults with high-risk acute graft v… Ended

2022-502673-41-01 High-Risk Acute Graft Versus Host Disease 2024-07-29
COACH: A Phase 2, Open-Label, Single-Arm, 156-week Trial to Investigate the Efficacy, Safety and Tolerability of Combined Once Weekly Navepe… Ended

2023-508341-40-00 Children with Achondroplasia 2024-07-26
Phase IIa Proof-of-Concept Study to Investigate the Efficacy, Safety, and Tolerability of FBL-MTX in Patients with Rheumatoid Arthritis Ended

2023-510258-17-00 Rheumatoid arthritis (RA) 2024-07-24
Ablative STEreotactic RadiOtherapy wIth Durvalumab (MEDI4736). An open label randomized phase II trial with durvalumab following Stereotacti… Ended

2024-512439-54-01 Non-small cell lung cancer (NSCLC) 2024-07-24
Single arm phase II study of ctDNA-guided encorafenib plus cetuximab retreatment in patients with BRAF V600E mutated mCRC. BRICKET study Ended

2023-509088-26-00 Metastatic colorectal cancer 2024-07-22
Phase 2 study of the infusion of differentiated autologous T-cells from peripheral blood, expanded and transduced with a lentivirus to expre… Ended

2024-515467-66-00 Acute lymphoblastic leukemia 2024-07-22
Antioxidant Treatment with Vitamin C in Cardiac Surgery Patients - A Pilot Randomized Controlled Trial Ended

2023-510561-10-00 Cardiovascular illness, Intensive care unit (ICU), open 2024-07-19
A phase II, open-label, multicenter study of orally administered RVU120 for the treatment of anemia in patients with lower-risk myelodysplas… Ended

2023-509947-29-00 Anemia in patients with very low, low or intermediate r 2024-07-18
HOVON 169 CAD: Phase II trial of Zanubrutinib in primary Cold Agglutinin Disease. CaZa study Ended

2023-505746-25-00 Cold agglutinin disease 2024-07-16
An Open-Label Study to Evaluate the Long-Term Safety, Tolerability and Efficacy of OMS906 in Patients with Paroxysmal Nocturnal Hemoglobinur… Ended

2023-507413-10-00 Paroxysmal Nocturnal Hemoglobinuria (PNH) 2024-07-16
An intensive program with quadruplet induction and consolidation plus tandem autologous stem cell transplantation in Newly Diagnosed High Ri… Ended

2023-509383-15-00 Multiple Myeloma 2024-07-05
A Phase 2b Study to Evaluate Eltrekibart in Adults with Moderate to Severe Hidradenitis Suppurativa Ended

2023-505608-43-00 Moderate to Severe Hidradenitis Suppurativa 2024-07-04
ACP-204 in Adults with Alzheimer’s Disease Psychosis Ended

2023-507325-42-00 Alzheimer Disease psychosis 2024-07-02
Safety and Impact of Dasatinib on Inflammation and AIDS virus in People under treatment Ended

2024-513714-36-01 Human immunodeficiency virus 2024-06-28
A phase II, randomized, open-label study comparing salvage radiotherapy in combination with 6 months of androgen-deprivation therapy (ADT) w… Ended

2024-512023-37-00 Prostate cancer 2024-06-27
Minimal Residual Disease-based Strategy with T-Cell Redirector After Treatment with Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone… Ended

2023-508310-41-00 Multiple myeloma 2024-06-26
MTR² Ended

2022-502790-42-00 Primary Central Nervous Lymphoma (PCNSL) 2024-06-24
TGF‐β And PDL‐1 inhibition with Bintrafusp alfa in Esophageal Squamous Cell carcinoma combined with chemoradiation TheRapY (TAPESTRY) Ended

2023-503312-32-00 Esophageal squamous cell carcinoma 2024-06-24
Breast cancer prevention in women at increased risk using low dose tamoxifen and/or diet and life style changes: a randomized 4 arms clinica… Ended

2023-503994-39-00 Healthy women aged 18-70 either carriers of a germline 2024-06-21
A 26-Week, Randomized, Double-Blind, Placebo-Controlled, Multi-center Study to Evaluate the Efficacy, Safety, and Tolerability of Axatilimab… Ended

2022-502954-15-00 Idiopathic pulmonary fibrosis 2024-06-21
Pyridoxine in primary sclerosing cholangitis Ended

2023-505155-47-00 Primary sclerosing cholangitis 2024-06-19
(Treatments to shrink tumors before surgery, radiation or other forms of nondrug therapy) to use the investigational drug (Darovasertib) in … Ended

2023-506683-14-00 Uveal Melanoma 2024-06-14