Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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An open-label, multi-center, phase 2 study of chemo-immunotherapy followed by reduced-dose hypofractionated RT and maintenance immunotherapy… Ended

2024-518408-32-00 Non Small Cell Lung Cancer 2024-12-03
Potential protective role of SGLT-2 inhibitors for chemotherapy-induced cardiotoxicity (PROTECT trial) Ended

2024-518611-18-00 Chemotherapy-induced cardiotoxicity in breast cancer 2024-12-03
Study to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 W… Ended

2023-505110-14-00 Colorectal Cancer 2024-12-02
A study looking at how effective and safe AZD7798 is in people with Crohn's disease Ended

2023-510487-12-00 Crohn's Disease 2024-11-29
Impact of microglial activation on synaptic density in Alzheimer’s disease Ended

2024-516566-11-00 Alzeihmer disease 2024-11-29
PErsonalized TREatment of high-risk MAmmary Cancer - the PETREMAC trial Ended

2024-519364-40-00 Breast cancer 2024-11-29
A study to test whether BI 764524 helps people with an eye condition called diabetic retinopathy Ended

2023-508891-12-00 Diabetic retinopathy 2024-11-28
L19IL2/L19TNF in skin cancer patients Ended

2024-518531-10-00 Phase II, open label, multicentric, proof-of-principle 2024-11-26
NEOadjuvant Abemaciclib and GIredestrant triaL in patients with ER-positive, HER2-negative Early breast cancer Ended

2023-510153-42-00 ER-positive, HER2-negative Early breast cancer 2024-11-25
Study of SKB264 to treat participants with advanced non-small cell lung cancer alone or as a combination treatment Ended

2023-507270-41-00 Advanced or Metastatic Non-small Cell Lung Cancer 2024-11-22
Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of Maridebart Cafraglutide in Adult Subjects With Type 2 Diabetes Mell… Ended

2024-513539-25-00 Type 2 Diabetes Mellitus 2024-11-22
An open-label extension multi-centre trial in adult subjects diagnosed with Type 1 diabetes mellitus exploring the effect of long-term Verap… Ended

2024-515234-33-00 Type 1 diabetes mellitus (T1D) 2024-11-21
Antidepressant effects of psilocybin in pharmaco-resistant depression Ended

2024-515899-13-00 pharmaco-resistant depression 2024-11-21
A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Severe to Very Severe Alopecia Areata Patients (Rezolve AA) Ended

2023-509981-39-00 Alopecia Areata 2024-11-20
A randomized, controlled study to evaluate LNP023 (iptacopan) in patients with active ANCA-associated vasculitis. Ended

2023-510525-15-00 active antineutrophilic cytoplasmic antibody (ANCA) ass 2024-11-18
RCT of Medical Cannabis Aerosol for DPNP Treatment Ended

2023-508932-68-00 Diabetic Peripheral Neuropathic Pain 2024-11-14
Therapeutic evaluation of low-dose IL-2-based immunomodulatory approach in patients with early Alzeihmer Disease Ended

2024-516565-36-00 Alzheimer Disease 2024-11-14
Prevention of cardiac Dysfunction during Adjuvant breast cancer therapy: A Randomized, Placebo-controlled, Multicenter Trial (PRADA-II) Ended

2024-515323-11-00 Heart Failure 2024-11-13
Sasanlimab Treatment As Bladder-Sparing Strategy For Patients With Muscle Invasive Bladder Cancer Ended

2024-511358-36-00 Molecularly Categorized Muscle Invasive Bladder Cancer 2024-11-11
A Phase 2 Study of an Anti-MTBR Tau Monoclonal Antibody in Participants with Early Alzheimer’s Disease Ended

2023-504840-32-00 Early Alzheimer’s Disease 2024-11-08
OPEN-LABEL EXTENSION STUDY TO ASSESS THE SAFETY AND LONG-TERM EFFECTIVENESS OF ORALLY ADMINISTERED EFAVIRENZ IN PATIENTS DIAGNOSED WITH ADUL… Ended

2023-505832-36-01 Type C Niemann-Pick Disease 2024-11-07
Phase II study of pembrolizumab in combination with cisplatin or carboplatin and pemetrexed as induction chemo+immunotherapy in resectable e… Ended

2023-509584-24-01 Malignant Pleural Mesothelioma 2024-11-06
A Randomized Phase 2 Study of Ocular Toxicity Evaluation and Mitigation During Treatment with Mirvetuximab Soravtansine in Patients with Rec… Ended

2023-505617-24-00 Recurrent Ovarian Cancer with High Folate Receptor-Alph 2024-11-05
Evaluation of the effect of a single dose of psilocybin on neural correlates of cognitive control in patients with CNEP (psychogenic nonepil… Ended

2023-509679-17-00 psychogenic non-epileptic seizures 2024-11-05