Phase II/III (Integrated)

402 trials 182 recruiting

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A randomized, double-blind, dose-ranging, placebo-controlled study to evaluate the efficacy and safety of PLN-74809 (bexotegrast) for the tr… Ended

2023-506185-31-00 Idiopathic pulmonary fibrosis (IPF) 2024-07-18
FDG-PET/CT versus conventional CT for response monitoring in metastatic breast cancer: A pilot study for a randomized clinical trial (MONITO… Ended

2023-506550-20-00 Metastatic breast cancer 2024-07-05
A study to test long-term treatment with spesolimab in people with a skin condition disease called hidradenitis suppurativa (HS) who took pa… Ended

2023-508377-82-00 Hidradenitis Suppurativa (HS) 2024-06-27
A study to learn if rozanolixizumab is safe, how it moves through the body, and if it works in children with myasthenia gravis Ended

2022-502074-16-00 Generalized Myasthenia Gravis 2024-06-14
Clinical trial of V940 and pembrolizumab in people with resectable locally advanced cutaneous squamous cell carcinoma Ended

2023-505712-37-00 The participants must have a histologically confirmed d 2024-06-06
A randomized, open label, multicenter phase II/III trial of sacituzumab govitecan compared to standard of care in metastatic, refractory col… Ended

2023-509771-17-00 Metastatic Colorectal cancer (mCRC) 2024-06-04
A clinical study of MK-6194 for the treatment of Systemic Lupus Erythematosus (SLE) (MK-6194-006) Ended

2023-505520-61-00 Systemic Lupus Erythematosus 2024-03-11
A Phase II/III Study of ABC008 to Determine Efficacy and Safety in IBM Ended

2022-501925-19-00 inclusion body myositis 2024-01-17
This is a clinical trial (study), to be conducted in several clinical sites worldwide, of an oral study drug which will be investigated in a… Ended

2023-503957-36-00 Moderate-to-Severe pruritus in adult subjects with nota 2023-12-04
A Phase IIb/III, Double-Blind, Randomised, Active-Controlled, Multi-Center, Non-Inferiority Clinical Trial, to assess the safety and immunog… Ended

2023-508458-25-00 COVID-19 disease 2023-11-13
Phase II-III study to assess the efficacy and safety of sublingual immunotherapy in patients suffering from grass pollen allergy Ended

2023-505880-35-00 Moderate-to-severe allergic rhinitis / rhinoconjunctivi 2023-11-10
A Phase 2 Safety, Tolerability, and Proof-of-Concept Study of VGL101 in Patients With Adult-Onset Leukoencephalopathy With Axonal Spheroids … Ended

2022-502505-15-00 Leukoencephalopathy 2023-11-09
A study to test whether spesolimab helps people with a skin disease called hidradenitis suppurativa Ended

2022-501074-19-00 Hidradenitis suppurativa 2023-10-13
A Clinical Study that will measure how well SEP-363856 works and how safe it is in adults with Generalized Anxiety Disorder Ended

2022-502077-42-00 generalised anxiety disorder 2023-09-14
Phase II-III study to assess the efficacy and safety of sublingual immunotherapy in patients suffering from birch pollen allergy Ended

2023-505567-37-00 Moderate-to-severe allergic rhinitis / rhinoconjunctivi 2023-08-22
Phase 2/3 Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancer Ended

2022-502196-31-00 Advanced or Recurrent Endometrial Cancer 2023-08-21
A study to test whether spesolimab helps people with skin disease called Netherton syndrome Ended

2022-501104-10-00 Netherton syndrome (NS) 2023-06-06
Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Oral Ozanimod in Pediatric Participants with Moderately to Severely Active Crohn… Ended

2023-508777-91-00 Moderately to Severely Active Crohn's Disease 2023-05-16
A study to evaluate the effects of Treprostinil Palmitil Inhalation Powder in participants with Pulmonary Hypertension with Interstitial Lun… Ended

2023-505540-19-00 Pulmonary Hypertension Associated with Interstitial Lun 2023-04-24
A study to test if izokibep improves psoriatic arthritis symptoms and to see how safe izokibep is Ended

2022-501362-22-00 Psoriatic Arthritis 2023-04-18
A 2-stage, Adaptive, Randomised, Double-blind, Placebo-controlled, Multicentre Study to Evaluate Dose and Treatment Effect of Pentosan Polys… Ended

2022-500228-31-01 Knee osteoarthritis pain 2023-03-31
Protocol Lay Person Short Title: A Trial of the Safety and Efficacy of Flexible Doses of SEP-363856 as Adjunctive Therapy in the Treatment o… Ended

2022-500538-27-00 Adjunctive therapy to antidepressants for the treatmen 2023-03-30
A multicenter, randomized, double-blind, placebo-controlled TRial evaluating Immunosuppressive treatment in patients with chronic virus-Nega… Ended

2024-512451-20-00 Patients with biopsy-proven virus-negative inflammatory 2023-02-28
Thiamine Against Chronic Rheumatoid Arthritis Fatigue Ended

2022-500922-13-00 Rheumatoid Arthritis 2023-02-16