Phase II/III (Integrated)

402 trials 182 recruiting

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An efficacy and safety study of 2-OHOA in patients with glioblastoma Ended

2024-511542-39-00 Newly diagnosed primary glioblastoma multiforme (ndGBM) 2019-09-16
AN OPEN-LABEL, MULTICENTER STUDY IN MALE PEDIATRIC PATIENTS WITH CEREBRAL X-LINKED ADRENOLEUKODYSTROPHY (CALD) TO ASSESS THE EFFECTS OF MIN-… Ended

2024-513774-21-00 CEREBRAL X-LINKED ADRENOLEUKODYSTROPHY (CALD) 2019-09-13
Efficacy and Safety of M281 in Adults with Warm Autoimmune Hemolytic Anemia: A Multicenter, Randomized, Double-blind, Placebo-controlled Stu… Ended

2023-505321-14-00 Warm Autoimmune Hemolytic Anemia 2019-09-06
KRT-232 Versus Best Available Therapy for the Treatment of Subjects With Myelofibrosis Who Are Relapsed or Refractory to JAK Inhibitor Treat… Ended

2024-513912-89-00 Primary Or Secondary (Post-PV MF or Post-ET-MF) Myelofi 2018-12-13
DANTE / FLOT8 A randomized, open-label Phase II/III efficacy and safety study of atezolizumab in combination with FLOT versus FLOT alone in … Ended

2024-514945-12-00 locally advanced resectable adenocarcinoma of the oesop 2018-09-03
First-in-human study of AT132 in X-Linked Myotubular Myopathy (XLMTM) Patients Ended

2024-512637-32-00 X-linked Myotubular Myopathy (XLMTM) 2018-08-21
A Study of the Efficacy and Safety of Guselkumab in Participants with Moderately to Severely Active Crohn's Disease Ended

2023-504736-18-00 Moderately to Severely Active Crohn's Disease 2018-07-26
A Study of Relatlimab plus Nivolumab Versus Nivolumab Alone in Participants with Advanced Melanoma Ended

2024-510913-13-00 Previously Untreated Metastatic or Unresectable Melanom 2018-05-18
Phase II umbrella study of novel anti-cancer agents in patients with NSCLC who progressed on an anti-PD-1/PD-L1 containing therapy. Ended

2023-509004-15-00 Patients with non-small cell lung cancer (NSCLC). 2018-02-20
ENRICH - Randomised, open label study of Rituximab/Ibrutinib vs Rituximab/Chemotherapy in older patients with untreated mantle cell lymphoma Ended

2024-514275-18-00 Mantle Cell Lymphoma (MCL) 2017-12-06
A Study Evaluating the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Patients with Advanced or Metastatic Non-Small C… Ended

2023-507500-31-00 Advanced or metastatic Non-small cell lung cancer (NSCL 2017-08-22
STAR-TREC: Can we Save the rectum by watchful waiting or TransAnal surgery following (chemo)Radiotherapy versus Total mesorectal excision fo… Ended

2024-516106-31-00 Early stage colorectal cancer 2017-06-16
Study to Evaluate Imetelstat (GRN163L) in Subjects with IPSS Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) Ended

2024-511348-25-00 Myelodysplastic syndromes (MDS) 2015-12-11
A clinical research study comparing two cisplatin dosing schedules combined with radiation for patients with advanced head and neck cancer. Halted

2024-515237-15-00 Advanced head and neck cancer 2025-01-21
A phase II/III multi-centre, open-label, parallel group study to prove the non-inferiority of safety and efficacy of Metronidazole/Neomycin … Halted

2024-518862-28-00 female patients with bacterial vaginosis (BV), respecti 2024-11-19
CD8 PET imaging study before and after CAR T-cell therapy Ended

2025-520560-18-00 Large B-cell lymphoma 2026-05-22
Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents with Sickle Cell Disease during Vaso-Occlusive Crisis Ended

2024-513440-29-00 Sickle cell disease vaso-occlusive crisis 2025-06-25
Phase II-III study to assess the efficacy and safety of subcutaneous cluster-immunotherapy in patients suffering from house dust mite allerg… Ended

2024-517014-15-00 Moderate-to-severe allergic rhinitis / rhino-conjunctiv 2025-05-07
Study of Oral Weekly GS-1720 and GS-4182 Compared With Biktarvy in People With HIV-1 Who Have Not Been Treated Ended

2024-512505-66-00 HIV-1 Infection 2025-03-03
A Double-Blind, Randomized, Multicenter, Trial Evaluating the Efficacy and Safety of PRAX-628 in Adults with Focal Seizures (POWER 1) Ended

2024-514559-13-00 Focal Epilepsy 2024-11-26
Efficacy, Safety and Tolerability of BHV-7000 in Subjects with Idiopathic Generalized Epilepsy with Generalized Tonic-clonic Seizures – SHIN… Ended

2023-508812-45-00 Idiopathic Generalized Epilepsy with Generalized Tonic- 2024-11-11
Cannabidiol for treatment of non-affective psychosis and cannabis use Ended

2024-517630-18-00 Lifetime cannabis use 2024-10-08
Multicenter, Prospective, Open-label, Randomized, Crossover Study to Evaluate Pharmacokinetics (PK), Safety, and Tolerability of TAK-881 in … Ended

2022-502095-23-01 Primary Immunodeficiency Diseases 2024-09-10
Phase II-III study to assess the efficacy and safety of subcutaneous cluster-immunotherapy in patients suffering from Olea europaea pollen a… Ended

2024-511383-88-00 Moderate-to-severe allergic rhinitis / rhinoconjunctivi 2024-09-01