Phase I – Other

1,082 trials 243 recruiting

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The Colder Fluids Study Ended

2023-506018-35-00 Hemodynamic parameters is to be investigated -- compari 2023-11-06
A Multiple Dose Pharmacokinetic Study of AMX0035 in Participants with Impaired Renal Function and in Healthy Participants Ended

2023-504393-37-00 Volunteers with Renal Impairment 2023-10-31
A Multiple Dose Pharmacokinetic Study of AMX0035 in Participants with Impaired Hepatic Function and in Healthy Participants Ended

2023-504397-38-00 Volunteers with Hepatic Impairment 2023-10-31
A randomized, double-blind, double dummy, placebo-controlled, four-way cross-over study to investigate the analgesic effects and CNS effects… Ended

2023-505793-15-00 Chronic pain 2023-10-30
A 3-Part Phase 1 Study to Investigate the Absolute Oral Bioavailability and Absorption, Metabolism, and Excretion of 14C-Unesbulin in Patien… Ended

2022-502118-10-00 Solid tumors 2023-10-27
A phase I randomized, investigator and participant-blind, adaptive, multiple-ascending dose, parallel and four-way crossover, placebo-contro… Ended

2023-504794-20-00 Healthy participants (part 1 and part 2) 2023-10-26
A trial to investigate the effect of acalabrutinib on skin prick test wheal size in adults with grass pollen allergy Ended

2023-505783-11-00 grass pollen allergy 2023-10-26
A Study to Learn if a Medicine That Reduces Stomach Acid Affects the Blood Level of Study Intervention Called Sisunatovir in Healthy Adults Ended

2023-507116-12-00 RSV 2023-10-25
A study to investigate the effect of ASTX660 (tolinapant) on the pharmacokinetics of substrates of OCT1, OCT2, and MATE1 in healthy voluntee… Ended

2023-503742-31-00 Not applicable. Healthy Volunteers 2023-10-23
An open-label, healthy subject, two-part study to assess the effect of verapamil on systemic exposure of EP395 (Part A), and to assess the e… Ended

2023-506345-34-00 Chronic obstructive pulmonary disease (COPD) 2023-10-23
MK-8507 Extended Multiple Dose Study Ended

2023-506697-12-00 HIV-1 infection 2023-10-20
Open label, single-center, four-part registration pharmacokinetic study: Part I: Pilot 2-way cross-over randomized, comparative pharmacokine… Ended

2023-507316-12-00 Narcolepsy with cataplexy 2023-10-20
A study in healthy men to test how BI 1810631 is taken up in the body when taken with or without food Ended

2022-502860-19-00 Healthy volunteer trial 2023-10-19
A Phase 1 Study of PRT2527 as Monotherapy and in Combination with Zanubrutinib or Venetoclax in Participants with Relapsed/Refractory Hemato… Ended

2022-502672-23-00 Richter's Syndrome 2023-10-18
A study to investigate JNJ-80202135 (nipocalimab) delivered subcutaneously via prefilled syringe autoinjector and via normal syringe Ended

2023-504280-16-00 Healthy Volunteers 2023-10-17
A study to investigate the safety, tolerability, pharmacokinetics, and early signs of biological activity of danegaptide following oral admi… Ended

2023-503683-16-00 Diabetic macular edema 2023-10-16
Pharmacokinetic Study of Single and Multiple Dose of PKL-021 Administered Orally to Healthy Subjects Ended

2023-506633-30-00 N/A submitted trial is conducted on healthy subjects 2023-10-13
MK-3508 Multiple Ascending Dose Study in Healthy Participants Ended

2023-505821-15-00 Respiratory syncytial virus infection 2023-10-12
Randomized, open-label, single dose, three-period, three treatment cross-over bioavailability study comparing test products Rosuvastatin/Eze… Ended

2023-507048-35-00 not applicable (submitted trial is bioavailability stud 2023-10-11
A Phase 1 Study to Assess Mass Balance, Pharmacokinetics, and Metabolism of [14C]Subasumstat in Patients With Advanced or Metastatic Solid T… Ended

2023-503449-79-00 Advanced or Metastatic Solid Tumours 2023-10-10
A study to investigate the effects of multiple doses of obefazimod on a combined oral contraceptive (ethinyl estradiol/drospirenone) in hea… Ended

2023-505297-15-00 Healthy female participants of childbearing potential. 2023-10-10
A clinical trial to learn how an investigational drug (norucholic acid) is absorbed, distributed, broken down, and removed from the body whe… Ended

2023-505862-27-00 Nonalcoholic fatty liver disease (NAFLD) 2023-10-10
A Phase I study to evaluate the pharmacokinetics, safety, and tolerability of multiple oral doses of obefazimod in patients with mild and mo… Ended

2023-505299-31-00 Ulcerative colitis and rheumatoid a1thritis 2023-10-09
A Study About Fazirsiran in People With and Without Liver Problems. Ended

2023-503735-17-00 Hepatic impairment. 2023-10-05