Major Depressive Disorder

32 total trials 14 recruiting

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Psilocybin's effects on anhedonia Not authorised

2023-509009-59-00 3
Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND) Pending

2024-516805-22-00 5
A randomized controlled trial of the effect of anesthetic dose during electroconvulsive therapy for major depression Pending

2024-519407-99-00 6
A Randomized, Delayed-Treatment Controlled, Phase 2 Pilot Study of Manualized MDMA-Assisted Therapy for Young Adults with Chronic Treatment- … Pending

2024-520319-42-01 4
Antidepressant effects of psilocybin without the psychedelic serotonin experience: A dimensional approach using functional neuroimaging. Pending

2025-521690-14-00 4
UNPRESCRIB-D Pending

2026-526314-90-00 6
An Open-label Study of Azetukalner in Major Depressive Disorder Recruiting

2025-523618-10-00 5 2026-06-04
A study for adolescents who are depressed and thinking of suicide Recruiting

2024-518615-19-00 5 2026-04-22
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder Recruiting

2025-523202-32-00 5 2026-02-26
Long-term study to assess the safety and tolerability of adjunctive NBI-1065845 in adults with Major Depressive Disorder (MDD) Recruiting

2024-519423-24-00 5 2025-10-07
DT-101 in Adults with Major Depressive Disorder Recruiting

2025-522784-15-00 4 2026-03-24
Psilocybin's effects on anhedonia Recruiting

2024-519265-22-00 3 2025-11-12
A Phase 3 Trial to Assess CYB003 in Major Depressive Disorder Recruiting

2024-519270-40-00 5 2025-10-30
Study to assess the efficacy and safety of adjunctive NBI-1065845 in adults with Major Depressive Disorder (MDD) Recruiting

2024-519420-25-00 5 2025-10-22
Study to assess the maintenance of effect of NBI-1065845 as an adjunctive treatment in participants with Major Depressive Disorder (MDD) Recruiting

2025-520541-72-00 5 2025-10-22
Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder Recruiting

2024-520333-68-00 5 2025-09-26
Study to assess the efficacy and safety of adjunctive NBI-1065845 in adults with Major Depressive Disorder (MDD) Recruiting

2024-519418-29-00 5 2025-09-19
Study to assess the efficacy and safety of adjunctive NBI-1065845 in adults with Major Depressive Disorder (MDD) Recruiting

2024-519421-37-00 5 2025-08-28
A study to assess the efficacy and safety of lumateperone in patients with major depressive disorder Recruiting

2023-503836-41-00 5 2025-03-10
A randomised, controlled trial to investigate the effect of a six-week intensified pharmacological treatment for major depressive disorder c … Recruiting

2023-506617-21-00 5 2024-08-29
Trial Examining Methods for Antidepressant Discontinuation (TEMPO) Recruitment ended

2024-511997-66-00 6 2024-11-22
Long-term Study to Assess the Safety and Effectiveness of NMRA-335140 in Participants with Major Depressive Disorder Recruitment ended

2023-505892-56-00 5 2024-09-30
CAPSI - Cancer related major depression treated with a single dose of psilocybin - a multicenter randomized placebo controlled double blind … Halted

2023-505532-35-00 4 2024-05-15
An Open-label Trial of Add-on Oral Slow-release Ketamine Treatment in Major Depression Ended

2025-524841-28-00 4 2026-03-13

Showing 1–24 of 32 trials