Calcium Electroporation for Urinary Bladder Tumors: A First-in-Human Feasibility, Safety, and Early Response Trial - The CALCIFER Trial

2026-526388-39-00 Human pharmacology (Phase I) - Other Authorised, recruitment pending

Status Authorised, recruitment pending · 1 EU/EEA countries · 1 sites

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Authorised, recruitment pending
Participants planned 20
Countries 1
Sites 1

Bladder cancer

Key facts

Sponsor
Region Sjaelland
Participant type
Patients
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Female Urogenital Diseases and Pregnancy Complications [C13], Analytical,Diagnostic,Therapeutic Techniques and Equipment [E]-Surgical Procedures, Operative [E04], Diseases [C] - Male Urogenital Diseases [C12], Diseases [C] - Neoplasms [C04]
Decision date (initial)
2026-07-03
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2026-526388-39-00
ClinicalTrials.gov
NCT07555769

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Bladder cancer

VersionLevelCodeTermSystem organ class
20.0 HLT 10046585 Urinary tract neoplasms malignant NEC 10029104
20.0 PT 10005003 Bladder cancer 100000004864
28.0 SOC 10038359 Renal and urinary disorders 18
20.0 HLGT 10038364 Renal and urinary tract neoplasms malignant and unspecified 10029104
28.1 HLT 10005013 Bladder neoplasms malignant 10029104
20.0 HLT 10046586 Urinary tract neoplasms unspecified malignancy NEC 10029104
20.0 HLT 10005058 Bladder neoplasms 10038359

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Region Sjaelland

Sponsor organisation
Region Sjaelland
Address
Sygehusvej 10
City
Roskilde
Postcode
4000
Country
Denmark

Scientific contact point

Organisation
Region Sjaelland
Contact name
Principal Investigator

Public contact point

Organisation
Region Sjaelland
Contact name
Principal Investigator

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Denmark Authorised, recruitment pending 20 1
Rest of world 0

Investigational sites

Denmark

1 site · Authorised, recruitment pending
Region Sjaelland
Department of Urology, Sygehusvej 10, 4000, Roskilde

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2026-04-15 Denmark Acceptable
2026-07-03
2026-07-03