A Phase 1 first-in-human study to evaluate SAR448272 in adult participants

2026-526014-87-00 Protocol SAD20279-MAD20280 Human pharmacology (Phase I) - First administration to humans Authorised, recruitment pending

Status Authorised, recruitment pending · 1 EU/EEA countries · 1 sites · Protocol SAD20279-MAD20280

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - First administration to humans
Status Authorised, recruitment pending
Participants planned 147
Countries 1
Sites 1

healthy volunteers

Key facts

Sponsor
Sanofi-Aventis Recherche & Developpement
Participant type
Patients, Healthy volunteers
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Immune System Diseases [C20]
Decision date (initial)
2026-06-19
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2026-526014-87-00
WHO UTN
U1111-1336-2172

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

healthy volunteers

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Sanofi-Aventis Recherche & Developpement

Sponsor organisation
Sanofi-Aventis Recherche & Developpement
Address
13 Quai Jules Guesde
City
Vitry Sur Seine
Postcode
94400
Country
France

Scientific contact point

Organisation
Sanofi-Aventis Recherche & Developpement
Contact name
Clinical Sciences and Operations

Public contact point

Organisation
Sanofi-Aventis Recherche & Developpement
Contact name
Clinical Sciences and Operations

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Germany Authorised, recruitment pending 147 1
Rest of world 0

Investigational sites

Germany

1 site · Authorised, recruitment pending
Charite Research Organisation GmbH
N/A, Chariteplatz 1, Mitte, Berlin

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2026-04-15 Germany Acceptable
2026-06-19
2026-06-19