A study to investigate the repeat-dose pharmacokinetics of a combined oral contraceptive when given alone and in combination with ganfeborole in female participants of non-childbearing potential.

2026-525790-39-00 Protocol 308245 Human pharmacology (Phase I) - Other Authorised, recruitment pending

Status Authorised, recruitment pending · 1 EU/EEA countries · 1 sites · Protocol 308245

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Authorised, recruitment pending
Participants planned 28
Countries 1
Sites 1

Tuberculosis

Key facts

Sponsor
Glaxosmithkline Research & Development Limited
Participant type
Healthy volunteers
Age range
18-64 years, 65+ years
Gender
Female
Therapeutic area
Diseases [C] - Bacterial Infections and Mycoses [C01]
Decision date (initial)
2026-07-06
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Tuberculosis

VersionLevelCodeTermSystem organ class
20.0 PT 10037440 Pulmonary tuberculosis 100000004862

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Glaxosmithkline Research & Development Limited

Sponsor organisation
Glaxosmithkline Research & Development Limited
Address
79 New Oxford Street
City
London
Postcode
WC1A 1DG
Country
United Kingdom

Scientific contact point

Organisation
Glaxosmithkline Research & Development Limited
Contact name
EU GSK Clinical Trials Call Center

Public contact point

Organisation
Glaxosmithkline Research & Development Limited
Contact name
EU GSK Clinical Trials Call Center

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Spain Authorised, recruitment pending 28 1
Rest of world 0

Investigational sites

Spain

1 site · Authorised, recruitment pending
Hospital Universitario La Paz
Servicio de Farmacología Clínica (UCICEC), Paseo De La Castellana 261, 28046, Madrid

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2026-03-31 Spain Acceptable
2026-06-29
2026-07-06
2 NON SUBSTANTIAL MODIFICATION NSM-1 2026-07-07 Spain Acceptable
2026-06-29
2026-07-07