Skin and Connective Tissue Diseases

445 trials 165 recruiting

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Dose-Ranging Efficacy Study of rapamycin cream applied topically in subjects diagnosed with port wine stains Recruiting

2025-520821-19-00 Subjects diagnosed with port wine stains 4 2024-01-02
Phase II, open label, single arm study of PembrolizumAb combiNeD with cisplatin or carbOplatin and etoposide in treatment naïve advanced meR… Recruiting

2022-500988-12-00 Advanced, naïve, Merkel cell carcinomas 4 2023-12-18
Contribution of an antiviral drug (Valaciclovir) in the treatment of generalized periodontitis (stage III or IV and grade A, B or C) Recruiting

2022-501957-35-00 Generalized periodontitis (stage III or IV and grade A, 5 2023-12-12
24 weeks double-blind randomized placebo-controlled trial to evaluate efficacy, PK, safety of LOU064 in adolescents (12 - <18) with CSU and … Recruiting

2022-502159-78-00 Chronic Spontaneous Urticaria 5 2023-12-06
Efficacy and tolerability of the combination of anifrolumab (300 mg IV) and phototherapy versus phototherapy in adults with progressive viti… Recruiting

2024-512041-17-00 Patient with non-segmental (symmetrical) vitiligo with 4 2023-11-27
Open-label, prospective study evaluating the efficacy and safety of Tirbanibulin 1% (Klisyri®) in the treatment of superficial basal cell ca… Recruiting

2023-505971-66-00 Superficial Basal cell carcinoma 10 2023-11-17
Hidradenitis Suppurativa: Evaluation of Upadacitinib in Adult and Adolescent Subjects Recruiting

2023-503661-28-00 Hidradenitis Suppurativa 5 2023-10-26
Optimization of atopic dermatitis treatment that requires second-line systemic therapy through multiomic predictive models of treatment resp… Recruiting

2023-506165-62-00 Atopic dermatitis 6 2023-09-25
Does peri-operative treatment with Tranexamic Acid reduce the early relapse rate for patients with melanoma; a randomised controlled trial Recruiting

2022-502633-26-00 Melanoma Surgery 5 2023-08-25
Clinical study to compare two cutaneous creams with the active substance methylprednisolone aceponate 0.1% and one cutaneous cream without a… Recruiting

2024-511390-30-00 Mild to moderate atopic dermatitis 5 2023-07-18
CAR-T cells in systemic B cell mediated autoimmune disease - CASTLE Recruiting

2024-516819-24-00 Systemic Sclerosis 9 2023-05-16
Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren Contracture Affecting the Metacarpophalangeal Joint. A Randomized … Recruiting

2022-501549-57-00 Dupuytren Concrature 5 2023-01-10
A phase-2 clinical trial of regorafenib in patients with pretreated advanced melanoma Recruiting

2024-514087-11-02 Melanoma 4 2022-10-03
Early detection of side effects in patients with metastatic melanoma receiving immune checkpoint inhibitor therapy by investigation of the C… Recruiting

2024-512219-37-00 melanoma 4 2022-09-06
Baricitinib in patients with relapsing or naïve dermatomyositis (BIRD) Recruiting

2024-511899-32-00 Dermatomyositis; Baricitinib in patients with relapsing 10 2022-08-31
Evaluating the Therapeutic Efficacy of Filgrastim in Severe Bullous Drug Eruptions (Lyell and Stevens-Johnson Syndromes) Recruiting

2024-515275-35-00 Lyell syndrome 10 2022-05-13
A prospective, randomized, multicenter, comparative study of the efficacy of imatinib resumption combined with atezolizumab versus imatinib … Recruiting

2022-503068-34-00 Metastatic Gastrointestinal Stromal Tumor 4 2022-04-06
Clinical study to compare the therapeutic effects of two ointments with the active substances clotrimazole and betamethasone dipropionate an… Recruiting

2022-501415-14-00 moderate to severely inflamed candidiasis of the skin 5 2022-03-08
Hydroxychloroquine in isolated cutaneous mastocytosis patients or indolent systemic mastocytosis with associated skin involvement patients: … Recruiting

2024-518594-33-00 mastocytosis 5 2021-11-18
Double-blind, randomised clinical study comparing efficacy and safety of Mecloderm® Cream (Test) vs. Lotricomb® Cream (Reference) vs. Vehicl… Recruiting

2024-514364-54-00 moderate to severely inflamed candidiasis of the skin 5 2021-10-18
Examination of medication-induced skin inflammation models and their use in the study of antibiotic concentration in inflamed, infected, and… Recruiting

2024-518477-34-00 Skin inflammation 3 2021-10-13
Clinical study to compare two cutaneous ointments with the active substance methylprednisolone aceponate 0.1% and one cutaneous ointment wit… Recruiting

2024-514548-10-01 Mild to moderate atopic dermatitis 3 2021-07-26
“A phase II, single arm study investigating neoadjuvant plus adjuvant treatment with Cemiplimab in surgically resectable, high risk stage II… Recruiting

2024-515204-39-00 surgically resectable, high risk stage III/IV (M0) Cuta 4 2021-02-10
Efficacy of bone marrow-derived stem cells in treatment of knee cartilage defects. Recruiting

2023-503486-32-00 Knee Cartilage Defect 4 2021-02-04