Nutritional and Metabolic Diseases

441 trials 157 recruiting

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Treatment of adult Wilson's Disease patients with gene therapy Ended

2023-509998-23-00 Wilson's Disease 7 2022-06-21
Study to evaluate the efficacy and safety of switching to insulin glargine 300 U/ml from insulin glargine 100 U/ml in patients with type 2 d… Ended

2024-518403-22-00 Diabetes mellitus II 6 2022-06-20
A research study investigating how semaglutide and dapagliflozin act in your body when dosed in one tablet Ended

2022-500007-52-00 Diabetes Mellitus, Type 2 2 2022-06-14
A study to learn how well the treatment combination of finerenone and empagliflozin works and how safe it is compared to each treatment alon… Ended

2023-506981-30-00 Chronic kidney disease in type 2 diabetes mellitus 4 2022-05-25
GliflOzin in eLderly Diabetic patiENts: A praGmatic intraclass Evaluation trial Ended

2024-518915-20-00 Type 2 diabetes mellitus 6 2022-02-16
An Phase 3 clinical study comparing a vector transferring the gene for Glucose-6-Phosphatase with placebo in adults with Glycogen Storage Di… Ended

2023-508750-25-00 Glycogen Storage Disease Type Ia (GSDIa) 5 2022-01-11
A clinical study to learn about the effects of a virus that transfers the gene for Glucose- 6-Phosphatase (G6Pase) in adults with Glycogen S… Ended

2023-504004-29-00 Glycogen storage disease type Ia 9 2021-10-18
Study to Evaluate the Long-Term Efficacy and Safety of the Investigational Drug LIB003 for the Reduction of Cholesterol in Patients with Hom… Ended

2023-510057-41-00 Patients With Homozygous and Heterozygous Familial Hype 5 2021-10-06
REGN7257 in Adult Patients with Severe Aplastic Anemia That Is Refractory to or Relapsed on Immunosuppressive Therapy Ended

2023-508601-24-00 Severe aplastic anemia (SAA) 7 2021-09-13
Metformin Intervention in children and adolescents with obesity. A parallel, three arms, randomized, 6 months, multi-center study with metfo… Ended

2024-517787-29-00 Children and Adolscents with obesity. 4 2021-09-09
Study Evaluating the Efficacy and Safety of Belapectin (GR-MD-02) for the Prevention of Esophageal Varices in NASH Cirrhosis Ended

2024-512619-28-00 Esophageal Varices in NASH Cirrhosis 10 2021-03-08
Prospective Study to Characterize the Pharmacokinetics and Pharmacodynamics of Cufence (Trientine Dihydrochloride) in Wilson Disease Patient… Ended

2024-516431-27-00 Wilson’s Disease 6 2021-02-23
Study to evaluate the effect and the safety of ladaraxin in adult and adolescent patients with recent onset type 1 diabetes Ended

2024-513560-26-00 Recent onset Type 1 Diabetes 4 2020-12-10
Octreotide treatment to improve nutritional recovery after surgery for patients with esophageal or gastric cancer, a prospective randomized … Ended

2022-502745-98-00 Esophageal and gastric cancer 4 2020-11-17
PIONEER TEENS. A research study to compare a new medicine oral semaglutide to a dummy medicine in children and teenagers with type 2 diabete… Ended

2023-506923-27-00 Type 2 diabetes 5 2020-10-30
A Phase 3 study of an Investigational Drug, Lumasiran (ALN-GO1) in patients with advanced primary hyperoxaluria Type 1 Ended

2023-503382-29-00 Primary Hyperoxaluria Type 1 (PH1) 5 2020-01-20
InSaKa trial: Insulin dextrose infusion versus nebulized salbutamol versus combination of salbutamol and insulin dextrose in acute hyperkale… Ended

2024-514889-40-00 Hyperkalemia 6 2019-12-20
Ertugliflozin Pediatric Study Ended

2022-501085-21-00 Type 2 Diabetes Mellitus 5 2019-11-29
Effects of the appetite-inducing hormone ghrelin on decision making in healthy volunteers Ended

2024-517598-26-00 Gambling disorder 4 2019-08-26
Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke Ended

2023-503673-38-00 Adults at high risk of cardiovascular events without pr 5 2019-05-24
PROLONGSTEM is a long term follow-up study of all the patients who have received at least one infusion of HepaStem Ended

2022-500251-22-00 This study will include all patients having received at 4 2018-04-12
Study to test the safety and the initial efficacy of an investigational medicinal product, abbreviated as AAV9-hSGSH, in children with Sanfi… Ended

2024-515835-31-00 Mucopolysaccharidosis type IIIA (Sanfilippo A syndrome) 7 2018-03-20
Markers of bonestatus in Diabetes Mellitus patients (type 1 and type 2) and the effect of antiresorptive treatment on glycemic markers Ended

2024-514148-99-00 Diabetes Mellitus and Osteopenia/Osteoporosis 6 2013-08-15
A Phase 3, Double-blind, Placebo-controlled, Randomized Withdrawal Study to Evaluate the Efficacy and Safety of SYNB1934 in Patients with PK… Ended

2022-502932-37-00 Phenylketonuria 5