Neoplasms

3,817 trials 1,526 recruiting

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A Study to Learn About the Study Medicine Called PF-07220060 in Combination With Letrozole in People Over 18 Years of Age With HR-Positive, … Ended

2024-512925-95-00 Advanced/Metastatic Breast Cancer 5 2025-05-16
A study of the PAN-KRAS inhibitor LY4066434 in participants with KRAS mutant solid tumors. Ended

2024-516733-12-00 Pancreatic Ductal Adenocarcinoma, Non-small Cell Lung C 1 2025-05-13
Phase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Subjects With Progressive Metastatic Castration-… Ended

2024-513968-25-00 Metastatic castration-resistant prostate cancer (mCRPC) 5 2025-04-28
A clinical study of pembrolizumab and other treatments for non-small cell lung cancer (MK-3475-01G) Ended

2024-515772-12-00 Lung neoplasm malignant (Stage IV Non-small cell lung c 4 2025-04-18
Study to test new drug eftilagimod alfa (also known as efti) combined with standard marketed treatments (pembrolizumab and chemotherapy) in … Ended

2024-513621-23-00 Advanced/metastatic non-small cell lung cancer (NSCLC) 5 2025-04-18
A Multicenter, Open-Label, Single-Arm, Phase II Trial Exploring the Maintenance of Trastuzumab and Pertuzumab Following Trastuzumab Deruxtec… Ended

2023-507306-13-00 HER2-positive unresectable locally recurrent or metasta 4 2025-04-13
Phase 3 study of RMC-6236 in patients with previously treated metastatic PDAC Ended

2024-516063-89-00 Metastatic Pancreatic Ductal Adenocarcinoma 5 2025-04-10
Clinical Trial of Cirtuvivint in Selected Advanced Soft-Tissue Sarcomas Ended

2024-511987-10-00 Selected Advanced Soft-Tissue Sarcomas 4 2025-04-07
A clinical study of raludotatug deruxtecan in people with gastrointestinal cancers (MK-5909-005) Ended

2024-517416-30-00 Gastrointestinal Cancers 10 2025-03-31
A study to learn if a combination of Fianlimab and Cemiplimab versus Cemiplimab alone is more effective for adult participants with Advanced… Ended

2022-501483-18-00 Advanced Non-Small Cell Lung Cancer 10 2025-03-28
BMS-986489 (BMS-986012 + Nivolumab Fixed Dose Combination) with Chemotherapy vs Atezolizumab with Chemotherapy as First-line Therapy in Part… Ended

2024-515740-23-00 Extensive-Stage Small Cell Lung Cancer (ES-SCLC) 5 2025-03-25
A Phase 1b/2, multicenter study of vorasidenib in combination with temozolomide (TMZ) in participants with IDH1- or IDH2-mutant glioma Ended

2024-513738-39-00 IDH1-mutant Glioma 9 2025-03-18
Efficacy of PErioperative PEmbrolizumab treatment in patients with resectable metastases from kidney cancer. The PE-PE study Ended

2024-512180-31-00 Oligometastatic renal cell carcinoma 4 2025-03-14
A clinical study to evaluate the Efficacy and Safety of Different Sequences of Ciltacabtagene Autoleucel (Cilta-cel), Talquetamab SC in Comb… Ended

2023-505792-71-00 Multiple Myeloma 4 2025-03-13
Phase I/II study of AGuIX nanoparticles with radiotherapy plus concomitant Temozolomide in the treatment of newly diagnosed glioblastoma Ended

2024-517114-15-00 newly diagnosed gliblastoma 7 2025-03-07
AMG 193 Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion (Master Protoco… Ended

2024-511253-21-00 Thoracic tumors with homozygous MTAP-deletion 3 2025-02-28
Phase 2/3 Randomized Study of INBRX-106 Add-on to Pembrolizumab in First-Line PD-L1 CPS ≥20 R/M HNSCC (HexAgon-HN) Ended

2024-515538-34-00 Head and Neck Squamous Cell Carcinoma 10 2025-02-27
A Phase 2 Study to Investigate Sonrotoclax combined with Zanubrutinib Versus Zanubrutinib alone in Patients With Previously Untreated Chroni… Ended

2024-513970-23-00 Previously Untreated Chronic Lymphocytic Leukemia 4 2025-02-27
Trial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of Care Docetaxel in Non-Small Cell Lung Cancer Ended

2024-512998-27-00 Non-Small Cell Lung Cancer 5 2025-02-21
DOVIPA, a phase II study evaluating efficacy and safety of DOstarlimab and oral VItamin D3 with folinic acid, 5FU, Irinotecan plus oxalipalt… Ended

2023-510004-49-00 non pretreated metastatic PAncreatic Cancer 4 2025-02-18
HOVON 172 MF: Study on tasquinimod treatment in patients with myelofibrosis Ended

2024-511565-11-00 Myelofibrosis 9 2025-02-12
STEP-WISE COMBINATION OF OBINUTUZUMAB, VEMURAFENIB AND COBIMETINIB IN PATIENTS WITH HAIRY CELL LEUKEMIA (HCL) PREVIOUSLY TREATED WITH PURINE… Ended

2024-520121-36-00 The following categories of HCL patients needing anti-l 4 2025-01-28
An interventional, open-label, Phase II study, to evaluate safety and efficacy of standard and high-dose chemotherapy associated with cranio… Ended

2024-518964-11-01 Metastatic medulloblastoma and other embryonal tumours 4 2025-01-27
Study aimed at testing the activity of a course of chemo-immunotherapy with retifanlimab combined with platinum-etoposide followed by surger… Ended

2024-516316-13-00 Merkel cell carcinoma without metastases in other organ 4 2025-01-21