Neoplasms

3,817 trials 1,526 recruiting

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A phase 2A pilot study to assess the safety and efficacy of eltanexor in relapsed/refractory NPM1-mutated acute myeloid leukemia Recruiting

2024-514724-16-01 Acute Myeloid Leukemia 4 2025-01-14
Neoadjuvant [177Lu]Lu-PSMAI&T radioligand therapy (PSMA-RLT) for patients with oligometastatic prostate cancer diagnosed using [68Ga]Ga-PSMA… Recruiting

2024-519377-18-00 Prostate Carcinoma 4 2025-01-14
An Ophthalmic Safety Study of New Investigational Drug in Breast Cancer Patients Recruiting

2024-512161-14-00 Breast Cancer 3 2025-01-14
Role of an hormonal vaginal therapy, the prasterone pessary, in the improvement of the vaginal/vulvar/urinary symptoms in menopausal women w… Recruiting

2023-506211-18-00 Postmenopausal women with previous breast cancer or cu 5 2025-01-09
A trial to learn how safe Dato-DXd is when given with osimertinib, and how well it works compared to osimertinib alone in people who have ad… Recruiting

2023-509883-89-00 Epidermal growth factor receptor (EGFR) mutation-positi 5 2025-01-09
MITO 31- A phase II trial of Olaparib in patients with recurrent ovarian cancer wild type for germline and somatic BRCA 1 and 2 genes: The M… Recruiting

2024-516841-38-00 recurrent ovarian cancer wild type for germline and som 4 2025-01-09
Olaparib beyond progression compared to platinum chemotherapy after secondary cytoreductive surgery in recurrent ovarian cancer patients. Th… Recruiting

2024-516842-21-00 Recurrent ovarian cancer 5 2025-01-09
177Lu-PSMA as a systemic adjuvant treatment in patients with high and very high risk prostate cancer after radical treatment with locoregion… Recruiting

2023-504912-13-00 Prostate Cancer 4 2025-01-09
Single microdose trial - CXCR4 PET tracer - Pharmacokinetics and pharmacodynamics of [68Ga]Ga-R54, a CXCR4-targeted radiopharmaceutical in p… Recruiting

2024-513303-14-00 Advanced solid neoplasm (breast, lung, colon, ovary, pa 1 2025-01-08
A phase II randomized clinical study of the combination of avelumab plus cetuximab as rechallenge strategy in pre-treated RAS/BRAF wild type… Recruiting

2024-519481-44-00 colorectal metastatic cancer 4 2025-01-08
Phase III trial of lomustine/temozolomide (TMZ) combination therapy vs. standard TMZ therapy for newly diagnosed MGMT promoter methylated gl… Recruiting

2023-506998-35-00 Glioblastoma 5 2025-01-08
Decreasing treatment for metastatic HER2-Positive Breast Cancer with undetectable cancer levels in blood tests Recruiting

2023-509811-98-00 Patients with HER2-positive locally advanced inoperable 4 2025-01-07
Sequential immunochemotherapy treatment with Pembrolizumab plus Dendritic Cell (DC) Vaccine followed by Trifluridine/Tipiracil plus Bevacizu… Recruiting

2024-514053-30-00 Metastatic colorectal cancer 4 2025-01-07
Interest of post-operative chemotherapy in patients with localized uterine leiomyosarcoma suspected to have a high-risk of relapse based on … Recruiting

2023-506350-21-00 Localized, resected, FIGO stage I (2018 classification) 4 2025-01-06
VICTOR: Venetoclax or Intensive Chemotherapy for Treatment Of Favourable Risk Acute Myeloid Leukaemia: a molecularly guided phase 2 study Recruiting

2024-516116-19-00 Acute Myeloid Leukaemia 4 2025-01-01
PROSPECTIVE EVALUATION OF THE DDR GENES ALTERATION TO PREDICT RESPONSE TO PLATINUM-BASED CHEMOTHERAPY IN ADVANCED UROTHELIAL CANCER Recruiting

2024-516450-21-00 metastatic or locally advanced urothelial cancer 6 2024-12-31
An Open-Label, Rollover Platform Study for Continued Study Treatment and Ongoing Safety Monitoring Recruiting

2024-515457-21-00 Non-Hodgkin lymphoma and chronic lymphocytic leukemia 3 2024-12-30
Phase 1, open-label, multicenter, dose escalation study of SRG-1505 as monotherapy in subjects with mature b-cell malignancies Recruiting

2023-505204-34-00 Mature B-Cell Neoplasm, Non-Hodgkin Lymphoma, Diffuse l 1 2024-12-30
Evaluating how well and how safely Alisertib works with hormone therapy in treating patients with breast cancer that has come back or spread… Recruiting

2024-511497-79-00 Hormone receptor positive (HR+), human epidermal growth 4 2024-12-30
HPV2-2303 - Phase 2 clinical trial evaluating secondary HPV vaccination after treatment of high-grade cervical lesions Recruiting

2024-513081-19-00 high-grade cervical intraepithelial lesions 4 2024-12-24
Efficacy and Safety of Anitocabtagene Autoleucel Versus Standard of Care Therapy in Participants With Relapsed/Refractory Multiple Myeloma Recruiting

2024-511188-26-00 Relapsed/refractory multiple myeloma in patients who ha 5 2024-12-20
Permanence of Indocyanine Green in axillary lymph nodes three weeks after subdermal injection in patients with Breast Carcinoma and metastat… Recruiting

2024-513163-57-00 Breast Cancer 4 2024-12-20
Study of the effectiveness of drugs selected depending on the molecular profile of diffuse intrinsic pontine glioma (DIPG). Recruiting

2024-515952-19-00 diffuse intrinsic pontine glioma 4 2024-12-18
Pasireotide as Maintenance Treatment with monthly deep intramuscular injection in SSTR2/3/5-Expressing Synovial Sarcoma and Desmoplastic Sma… Recruiting

2024-511935-86-00 Locally advanced or metastatic synovial sarcoma ICD-O3, 4 2024-12-18