Universitair Medisch Centrum Groningen — Sponsor Intelligence | 71 EU Trials

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71 Registered trials

36 Recruiting

19 Completed trials

10 Countries active

88 Unique IMPs

100% Results reported

Phase III

Phase II

Phase IV

Phase I

Phase III: 10 Phase II/III: 1 Phase II: 21 Phase I/II: 5 Phase III/IV: 3 Phase IV: 14 Phase I: 8 Phase I (Other): 5 Phase I (FiH): 4

Oversight events:

1 temporary halt 1 corrective measure across 2 trials

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100%

19 of 19 completed trials have published summary results (EU CTR Article 37 — 12-month obligation).

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Top indications

Rectal cancer 1 Albuminuria 1 Glioblastoma 1 Polymyalgia rheumatica 1 Giant cell arteritis 1 Endometrial cancer 1 Polycystic liver disease 1 Chronic kidney disease 1 Inflammatory bowel disease 1

Top IMPs

(S)-2,2',2''-(10-(2-(4-(3-((4-(2-(2-CYANO-4,4-DIFLUOROPYRROLIDIN-1-YL)-2-OXOETHYLCARBAMOYL)-QUINOLIN-6-YL)(METHYL)AMINO)-PROPYL)PIPERAZIN-1-YL)-2-OXOETHYL)-68GA-[1,4,7,10]-TETRAAZACYCLODODECANE-1,4,7-TRIYL)TRIACETATE 4 BEVACIZUMAB 3 FINERENONE 3 ADALIMUMAB 2 ATEZOLIZUMAB 2 EMPAGLIFLOZIN 2 EVEROLIMUS 2 IOHEXOL 2 MYCOPHENOLATE MOFETIL 2 PEMBROLIZUMAB 2 RISANKIZUMAB 2 TACROLIMUS 2

All trials — page 2

71 total

A phase I study investigating the local tolerability and pharmacokinetics of isoniazid (INH) inhalation by wet nebulization in patients with… Recruiting

2024-517793-25-00 Phase I 1 country
FINE-START; A parallel-group, randomized, prospective, interventional, double-blind, multicenter global Phase 3 study to investigate the eff… Recruiting

2025-523075-32-00 Phase III 1 country FINERENONE
method VALIDation and evaluation of non-radioactive methods to measure Glomerular Filtration Rate Recruiting

2023-509156-34-02 Phase IV 1 country CLEMASTINE; EPINEPHRINE; IOHEXOL
Evaluating PD-1/PD-L1 in rectal cancer by quantitative fluorescence molecular endoscopy. Recruiting

2023-507106-13-00 Phase I 1 country
Pilot Study on Subcutaneously Administered Immunotherapy for the Treatment of Cervical Cancer Recruiting

2025-521771-31-00 Phase I (Other) 1 country
Towards improved therapy selection and targeted treatment for nasopharyngeal carcinoma. A proof-of-concept pilot study for somatostatin rece… Recruiting

2025-520689-23-00 Phase I/II 1 country GALLIUM (68GA) EDOTREOTIDE
PsyPal; Psilocybin Therapy for Psychological Distress in Palliative Patients Recruiting

2023-510488-36-01 Phase II 4 countries PSILOCYBINE
CD8 PET imaging in metastatic solid tumours; A phase II, open label, multi-center study of 89Zr-DF-crefmirlimab for CD8 positron emission to… Recruiting

2024-515885-15-00 Phase I/II 2 countries CETRELIMAB; NIVOLUMAB; ZIRCONIUM (89ZR) CREFMIRLIMAB BERDOXAM
Takeda Brentuximab; Molecular Imaging of Zirconium-89-labeled Brentuximab as a Tool to Investigate brentuximab biodistribution in CD30-posit… Recruiting

2024-511151-18-01 Phase I (Other) 1 country
Assessment of the value of FAPI and FDG-PET-CT in the diagnosis of acute phase Peyronie’s Disease Recruiting

2024-518838-82-00 Phase IV 1 country (S)-2,2',2''-(10-(2-(4-(3-((4-(2-(2-CYANO-4,4-DIFLUOROPYRROLIDIN-1-YL)-2-OXOETHY…
LAG3 PET; ImmunoPET imaging with 89Zr-DFO-REGN3767 in patients with advanced solid cancer prior to and during treatment with cemiplimab with… Recruiting

2024-516795-15-00 Phase II 1 country CEMIPLIMAB; FIANLIMAB
Imaging of inflamed arteries in giant cell arteritis and inflamed joints in rheumatoid arthritis with a PET/CT scan. Recruiting

2024-514489-38-01 Phase II 1 country ZIRCONIUM (89ZR) CREFMIRLIMAB BERDOXAM
Detection of tumor tiSsue in pEritoneal metastases of coLorectal origin using a VEGF-targeted optical fluoresCent imaging tracer during diag… Recruiting

2024-517718-13-01 Phase I (Other) 1 country
[68Ga]-FAPI PET/CT to visualize the activity of fibrogenic cells in patients with non-resolving shock lung. Recruiting

2024-517257-27-00 Phase III/IV 1 country (S)-2,2',2''-(10-(2-(4-(3-((4-(2-(2-CYANO-4,4-DIFLUOROPYRROLIDIN-1-YL)-2-OXOETHY…
Macrophage imaging GCA Recruiting

2024-514491-40-00 Phase II 1 country [18F]FLUORO-PEG-FOLATE
Subtyping Primary Aldosteronism with Para-chloro-2-[18F]fluoroethyl-etomidate ([18F]CETO) Recruiting

2023-508254-26-00 Phase I (FiH) 1 country
RESTART; Autologous Transplantation of Adult Salivary Gland Stem Cells to Restore Submandibular Gland Function after Radiotherapy Recruiting

2024-512968-57-00 Phase I 1 country
Small patient study to explore the anticancer effect of cannabis oil in untreatable patients with liver cancer Recruiting

2024-514049-13-02 Phase II 1 country
GREAT; GRoningen Early-PD Ambroxol Treatment Trial Recruiting

2024-514976-41-00 Phase II 1 country
FREE-study Recruiting

2024-516277-68-00 Phase IV 3 countries
Treatment with leflunomide in patients with polymyalgia rheumatica Recruiting

2024-514210-12-00 Phase III 1 country LEFLUNOMIDE
STRATIFY; Near-infrared fluorescence molecular imaging of adalimumab-800CW to elucidate the drug distribution throughout inflamed tissue in … Recruiting

2024-513390-50-00 Phase I (Other) 1 country
Safety and feasibility of immuno-OCT Recruiting

2023-506395-27-00 Phase I/II 1 country BEVACIZUMAB
eGPA and local inflammation within the ENT area Recruiting

2023-508029-28-00 Phase IV 1 country

Showing 25–48 of 71 trials

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