Leids Universitair Medisch Centrum (LUMC) — Sponsor Intelligence | 33 EU Trials

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33 Registered trials

17 Recruiting

10 Completed trials

1 Countries active

42 Unique IMPs

100% Results reported

Phase II

Phase I/II

Phase IV

Phase III: 2 Phase II/III: 2 Phase II: 5 Phase I/II: 4 Phase III/IV: 3 Phase IV: 11 Phase I: 2 Phase I (Other): 1 Phase I (FiH): 3

100%

10 of 10 completed trials have published summary results (EU CTR Article 37 — 12-month obligation).

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Top indications

Malaria immunisation 3 Heart transplant 1 Liver transplant 1

Top IMPs

SODIUM CHLORIDE 3 PEMBROLIZUMAB 2 TIL CELLS 2 [AL[18F]F]FAPI-74 1 6QC-ICG 1 ALPHA-TOCOPHEROL 1 B/PHUKET/3073/2013 - LIKE STRAIN (B/PHUKET/3073/2013, MEDI 306444), INFLUENZA VIRUS B/AUSTRIA/1359417/2021 - LIKE STRAIN (B/AUSTRIA/1359417/2021, MEDI 355292), A/DARWIN/9/2021 (H3N2) - LIKE STRAIN (A/NORWAY/16606/2021, MEDI 355293), INFLUENZA VIRUS A/VICTORIA/4897/2022 (H1N1)PDM09 - LIKE STRAIN (A/NORWAY/31694/2022, MEDI 369815) 1 B/PHUKET/3073/2013-LIKE VIRUS (B/PHUKET/3073/2013, WILD TYPE), INFLUENZA VIRUS B/MICHIGAN/01/2021, INFLUENZA A/VICTORIA/4897/2022 IVR-238 (H1N1), INACTIVATED, INFLUENZA VIRUS A/CALIFORNIA/122/2022 SAN-022 (H3N2) STRAIN (SPLIT, INACTIVATED) 1 BEVACIZUMAB ZIRCONIUM ZR-89 1 C1 ESTERASE INHIBITOR (HUMAN) 1 CABOZANTINIB 1 DULOXETINE 1

All trials — page 2

33 total

CIAO@TBI Ended

2024-514488-24-02 Phase II 1 country C1 ESTERASE INHIBITOR (HUMAN); SODIUM CHLORIDE
Studying the LAIV induced Immune respOnse in the Nasopharynx of young children. Ended

2024-513933-18-00 Phase IV 1 country INFLUENZA VIRUS B/AUSTRIA/1359417/2021 - LIKE STRAIN (B/AUSTRIA/1359417/2021, ME…
(IPCOM) Influence of Proton pump inhibitor CO-medication on the absorption of innovator and generic formulations of Mycophenolate mofetil Ended

2024-517043-32-00 Phase IV 1 country MYCOPHENOLATE MOFETIL; PANTOPRAZOLE
Durability of protection after single immunisation with genetically attenuated Plasmodium falciparum ∆mei2 (GA2) sporozoites – a follow-up, … Ended

2024-513516-99-00 Phase I/II 1 country
YF_PROTECT: Prophylactic treatment with sofosbuvir for Yellow Fever Ended

2024-510949-34-00 Phase IV 1 country SOFOSBUVIR
Repeated corticosteroid injections around the Greater Occipital Nerve (GON) as prophylactic treatment in chronic cluster headache Ended

2024-514311-10-00 Phase III 1 country METHYLPREDNISOLONE ACETATE; SODIUM CHLORIDE
Neo-adjuvant Pembrolizumab in vulvar squamous cell carcinoma: a clinical proof-of-concept study Ended

2024-512862-32-00 Phase II 1 country PEMBROLIZUMAB
Reversal of opioid-induced respiratory depression with opioid antagonists - a pharmacokinetic pharmacodynamic modeling study in opioid naïve… Ended

2024-518041-16-00 Phase IV 1 country FENTANYL CITRATE; NALMEFENE HYDROCHLORIDE; NALOXONE HYDROCHLORIDE; ONDANSETRON H…
A Randomized, open label, Non-inferiority trial on the efficacy of Lacosamide versus Duloxetine in Patients with Chemotherapy-induced Polyne… Ended

2024-511008-17-00 Phase IV 1 country DULOXETINE; LACOSAMIDE

Showing 25–33 of 33 trials

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