Centre Hospitalier Universitaire De Nantes — Sponsor Intelligence | 196 EU Trials

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196 Registered trials

101 Recruiting

50 Completed trials

7 Countries active

292 Unique IMPs

100% Results reported

Phase III

Phase II

Phase IV

Phase III: 54 Phase II/III: 10 Phase II: 70 Phase I/II: 8 Phase III/IV: 8 Phase IV: 29 Phase I: 3 Phase I (Other): 7 Phase I (FiH): 6 Other: 1

Oversight events:

1 serious breach 7 temporary halts 1 urgent safety measure 1 corrective measure across 10 trials

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100%

50 of 50 completed trials have published summary results (EU CTR Article 37 — 12-month obligation).

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Top indications

Asthma 3 Hepatocellular carcinoma 3 Parkinson's disease 2 Chronic kidney disease 2 Vitiligo 2 Alcohol use disorder 2 Epidermolysis bullosa 2 Cerebral haemorrhage 1 Colorectal cancer metastatic 1 Endometriosis 1 Hepatectomy 1 Intensive care 1

Top IMPs

SODIUM CHLORIDE 9 TACROLIMUS 5 MYCOPHENOLATE MOFETIL 4 PSILOCYBINE 4 AMOXICILLIN, CLAVULANIC ACID 3 BORTEZOMIB 3 CLOSTRIDIUM BOTULINUM NEUROTOXIN TYPE A (150KD), FREE OF COMPLEXING PROTEINS 3 ISATUXIMAB 3 KETAMINE HYDROCHLORIDE 3 LENALIDOMIDE 3 MYCOPHENOLIC ACID 3 N,N-DIETHYL-(2-(4-(2-(18F)FLUOROETHOXY)PHENYL)-5,7-DIMETHYLPYRAZOLO(1,5-A)PYRIMIDINE-3-YL)ACETAMIDE 3

All trials — page 5

196 total

Dose escalation of allogeneic Adipose derived Stroma/stem Cells for the treatment of Crohn’s fistula Recruiting

2024-511821-75-00 Phase I (FiH) 1 country
MAESTRO-4MS : "Allogenic Adipose tissue-derived Mesenchymal Stromal Cells for the treatment of Primary Progressive Multiple Sclerosis: an op… Recruiting

2023-509538-20-01 Phase I 1 country
Betamethasone meniscal infiltration under ultrasound control: a randomized, double-blind, placebo-controlled multicenter trial. Recruiting

2023-510079-74-00 Phase III 1 country BETAMETHASONE DIPROPIONATE, BETAMETHASONE SODIUM PHOSPHATE; LIDOCAINE HYDROCHLOR…
Eight-Treg study: a phase I dose escalation trial of adoptive immunotherapy with autologous ex vivo expanded regulatory CD8+ T cells in livi… Recruiting

2024-513771-40-01 Phase I (FiH) 1 country CETIRIZINE DIHYDROCHLORIDE; EIGHT TREG; METHYLPREDNISOLONE HYDROGEN SUCCINATE; M…
An open single-center, phase I proof of concept trial to assess the safety and feasibility of adoptive cell therapy with autologous EBV-spec… Recruiting

2024-515563-55-00 Phase I (Other) 1 country
ASIC Channels and Migraine Disease - Proof-of-Concept Study on the Efficacy of Amiloride in Migraine Aura Prophylaxis Recruiting

2024-516044-25-00 Phase II/III 1 country AMILORIDE HYDROCHLORIDE DIHYDRATE
Interest of Oxytocin as an Adjuvant Treatment of Psycho-educational Measures in Challenging Behaviors in Children With Autism Spectrum Disor… Recruiting

2024-516306-28-00 Phase II/III 1 country
Multicentric Phase 1 Study With Escalation of Doses of Daratumumab in Combination With Chemotherapy (Idarubicin and Cytarabine) or CPX-351 … Recruiting

2022-502585-25-00 Phase I (Other) 1 country
Intravenous Dexmedetomidine as an Adjuvant to Locoregional Anesthesia in Pediatric Surgery: A Prospective, Randomized, Double-Blind, Placebo… Recruiting

2024-514550-73-00 Phase II 1 country
Phase 2 study evaluating the efficacy of injectable gentamicin in hereditary ichthyosis - GENTIC Recruiting

2023-505570-15-00 Phase II 1 country GENTAMICIN SULFATE
EBUL0. A 20-Week Multicentre, Open Study Assessing the Efficacy and Safety of Apremilast in Patients > 6 years of age with Epidermolysis bul… Recruiting

2023-508794-83-00 Phase II 1 country APREMILAST; APREMILAST, APREMILAST, APREMILAST
Prospective, multicenter, randomized, open-label, parallel-group controlled phase 3 study of tacrolimus minimization in kidney transplant re… Recruiting

2022-502624-44-00 Phase III 3 countries IOHEXOL; MYCOPHENOLATE MOFETIL; MYCOPHENOLIC ACID; PREDNISOLONE METASULFOBENZOAT…
Study of Artificial Intelligence-based Personalized Rituximab Treatment Protocol in Membranous nephropathy - iRITUX Recruiting

2024-510718-34-00 Phase III/IV 1 country RITUXIMAB
Study of posaconazole prophylaxis in patients receiving hematopoietic stem cell allograft (allo-HSC) at high risk of invasive fungal infecti… Recruiting

2024-511507-42-00 Phase II 1 country POSACONAZOLE
MYELOFLUDATEP: Exploratory study evaluating the value of 18F-Fludarabine PET for the initial or relapsed assessment and therapeutic evaluati… Recruiting

2024-515219-23-00 Phase I (Other) 1 country
Multicenter randomized, double-blind, placebo controlled trial evaluating the effect of a 30-week caffeine treatment on cognition in early-t… Recruiting

2024-514099-41-00 Phase III 1 country CAFFEINE
Comparison of topical hydrocortisone versus dexamethasone treatment for inflammatory secretions of the conjunctiva in patients with ocular p… Recruiting

2024-517441-14-00 Phase III/IV 1 country DEXAMETHASONE PHOSPHATE; HYDROCORTISONE SODIUM PHOSPHATE; POVIDONE
Phase I/II study assessing radioligand therapy (RLT) using 177Lu-PentixaTher for relapsed/refractory CXCR4+ acute leukemia. Recruiting

2022-501019-15-00 Phase I/II 1 country
LONG-TERM EFFECTIVENESS AND SAFETY EVALUATION OF OCRELIZUMAB IN FRENCH PATIENTS WITH PROGRESSIVE MS: CONSONANCE EXTENSION STUDY Recruiting

2024-516433-13-00 Phase III 1 country
Randomized Phase 2 study testing two conditioning regimen with a single prophylaxis of graft-versus-host disease by cyclophosphamide and met… Recruiting

2023-509042-35-01 Phase II 1 country
EXLIBRIS : “EXL-01 combined with nivolumab for advanced NSCLC refractory to immunotherapy” Recruiting

2023-505285-28-01 Phase I/II 1 country EXL01; NIVOLUMAB
Pathophysiology of pain in Parkinson's disease: exploration of the serotonin system in positron emission tomography Recruiting

2022-501123-24-00 Phase II 1 country 4-FLUORO-N-[2-[4-(2-METHOXYPHENYL)PIPERAZIN-1-YL]ETHYL]-N-PYRIDIN-2-YLBENZAMIDE
Avoid With locoregional Analgesia Persistant Postoperative Pain After Surgery In Children Recruiting

2023-503499-25-00 Phase IV 1 country DEXAMETHASONE PHOSPHATE; IBUPROFEN; KETOPROFEN; MEPIVACAINE HYDROCHLORIDE; MORPH…
Amoxicillin alone versus amoxicillin/clavulanate for community-acquired pneumonia in patients aged 65 years or older, and hospitalized in a … Recruiting

2023-503645-63-00 Phase III 1 country AMOXICILLIN; AMOXICILLIN, CLAVULANIC ACID

Showing 97–120 of 196 trials

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