Therapeutic Use (Phase IV)

1,197 trials 558 recruiting

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AFAMOSI: Prospective, randomized, multicenter Phase IV study to evaluate the efficacy and safety of afatinib followed by osimertinib compare… Ended

2024-511625-55-00 EGFRmutated/T790M Mutation negative non-squamous NSCLC 2022-11-30
OM 85 in Paediatric Recurrent Respiratory Tract Infections with Wheezing Lower Respiratory Illness Ended

2024-511581-37-00 Respiratory Tract Infections with Wheezing Lower Respir 2022-11-25
A Phase 4, Multi-centre, Randomized, Evaluator-blinded, Active-controlled Study to Determine the Incidence of Squamous Cell Carcinoma and Ev… Ended

2024-514394-22-00 Actinic Keratosis 2022-10-24
A randomized, two-armed, single-blind, parallel, active controlled, and non-inferiority clinical trial to Compare Efficacy and Safety of ant… Ended

2024-515557-22-00 Juvenile Idiopathic Arthritis 2022-10-01
Optimization of Cyclosporin therapy in atopic dermatitis through multiomic predictive models of treatment response (DermAtOmics) Ended

2022-500677-14-00 Adult, adolescent and paediatric patients with moderate 2022-09-28
Master Protocol for Encorafenib/Binimetinib Continuation Sub-Studies (FLOTILLA Study) Ended

2023-509408-13-00 Solid tumors 2022-09-20
Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adult Patients with Uncontrolled Moderate to Sev… Ended

2024-513423-16-00 Asthma 2022-08-25
A multicenter, open-label, controlled study to investigate the effect of either LF111 or Drospirenone chewable tablets on bone mineral densi… Ended

2024-512347-23-00 Oral contraception 2022-08-22
Lorlatinib Continuation Study Ended

2023-508952-21-00 Lung cancer 2022-08-02
A post-trial access roll-over study to allow access to ribociclib (LEE011) for patients who are on ribociclib treatment in Novartis-sponsore… Ended

2024-514891-41-00 HR+, HER2- advanced or metastatic breast cancer 2022-07-19
Avalglucosidase alfa French post-trial access for participants with Pompe disease Ended

2024-514773-22-00 Glycogen storage disease type II 2022-07-11
The RESCUE study Ended

2024-518272-30-00 Glucocorticoid induced adrenal insufficiency 2022-06-01
LEGACY Ended

2023-504360-42-00 Non-ST-segment elevation acute coronary syndrome 2022-05-13
Efficacy study of osimertinib in treatment-naïve patients with EGFR mutant NSCLC according to TP53 mutational status (TEMPLE-2) Ended

2024-517424-18-00 Patients with EGFR mutant NSCLC according to TP53 muta 2022-05-10
Efficacy, tolerability and preferences of per oral or subcutaneous methotrexate in patients with early rheumatoid arthritis – a randomised r… Ended

2024-512453-25-00 Rheumatoid arthritis 2022-04-28
Combination of Abemaciclib and endocrine therapy in hormone receptor positive HER2 negative locally advanced or metastatic breast cancer wit… Ended

2024-511209-49-00 Patients with hormone receptor positive HER2 negative l 2022-04-26
A Study to Evaluate Overall Health, Physical Activity and Joint Outcomes, in Participants with Severe or Moderate Hemophilia A without FVIII… Ended

2023-505747-40-00 Severe or Moderate Hemophilia A 2022-04-20
NOR-CACTUS Ended

2024-511223-34-00 Carpal Tunnel Syndrome 2022-04-08
Postmarketing Parallel Randomized Clinical Trial to Determine the Efficacy and Safety of Atropine and DIMS Lenses in the Control of Myopia i… Ended

2024-514651-15-00 Myopia 2022-02-16
Low dose cisplatin weekly versus high dose cisplatin every three weeks in primary chemoradiation in sarcopenic head and neck cancer patients Ended

2024-514919-10-00 Locally advanced head and neck squamous cell carcinoma 2022-01-24
Management of moderate POstoperative recurrence in Crohn's disease: a randoMizEd contROLled trial of therapeutic escalation, the POMEROL tri… Ended

2023-508242-18-00 Crohn's disease 2021-12-21
Withdrawal of Pharmacological Treatment in Patients Responding to Cardiac Resynchronization Therapy: (REMOVE) Ended

2023-504946-70-00 Heart Failure 2021-12-01
Zoledronate Early to Hip Fractures Patients – safe and effective? A Randomized controlled double-blinded treatment strategy trial on Zoledro… Ended

2023-510198-32-00 Hip fracture 2021-12-01
Randomized clinical trial assessing the value of Beta-Blockers and Antiplatelet Agents in patients with Spontaneous Coronary Artery Dissecti… Ended

2024-516039-28-00 Spontaneous Coronary Artery Dissection. 2021-09-28