Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

Filter these 3,454 trials by condition, country, sponsor and more.

Open in Search →

SIRIUS Sarcoidosis with moderate to severe facial skin involvement: an open multicenter study of the efficacy and safety of oral sirolimus Ended

2024-514609-76-00 Adult patients (men and women) (≥ 18 years of age) with 2022-11-23
The WILLOW LTE study with enpatoran in participants with SCLE, DLE and/or SLE Ended

2024-510871-39-00 Systemic lupus erythematosus (SLE) and cutaneous lupus 2022-11-21
[68Ga]Ga-ABY-025 PET in solid tumors Ended

2022-500448-39-00 Gastro-esophageal cancer with HER2-expression (cohort 1 2022-11-20
Study of pembrolizumab, lenvatinib and chemotherapy combination in first line lung cancer Ended

2024-511412-25-00 First line treatment for extensive-stage small cell lun 2022-11-07
A study into the efficacy and safety of dazucorilant (CORT113176) in patients with Amyotrophic Lateral Sclerosis Ended

2024-514082-19-00 Amyotrophic Lateral Sclerosis 2022-11-04
Radiotherapy in combination with pembrolizumab in patients with PSA persistence or biochemical recurrence after radical prostatectomy due to… Ended

2024-513633-20-00 recurrent prostate cancer 2022-10-28
Ixekizumab Diabetes Intervention Trial (I-DIT) Ended

2023-508588-58-00 Diabetes type 1 2022-10-25
A Phase 2 Study of Isatuximab in combination with Pomalidomide and Dexamethasone in MM Patients who received one prior line of therapy conta… Ended

2024-516060-28-00 Multiple myeloma patients who received one prior line o 2022-10-17
Reduction of hormone therapy duration in women with hormonesensitive breast cancer at very low risk of metastatic recurrence Ended

2024-514480-26-00 Post-menopausal women with localized luminal A breast c 2022-10-12
I-DXd in Patients With Pretreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC) Ended

2024-512368-79-00 Pretreated Extensive-stage Small Cell Lung Cancer (ES-S 2022-10-10
METIMMOX-2: Oxaliplatin Chemotherapy and Immunotherapy to Patients with the Common pMMR/MSS Type of Large Bowel Cancer Spread to Other Organ… Ended

2022-500027-76-00 Colorectal cancer 2022-10-05
Multicenter, phase II, national and open-label study to evaluate Iberdomide-dexamethasone alone or in combination with standard MM treatment… Ended

2024-518870-15-00 Multiple Myeloma 2022-10-03
SURE-02_An open label, single-arm, phase 2 study of perioperative pembrolizumab plus sacituzumab govitecan, and bladder-saving approach, for… Ended

2024-514569-20-00 muscle-invasive bladder cancer 2022-09-15
A safety and efficacy study of treatment combinations with and without chemotherapy in adult patients with advanced upper gastrointestinal t… Ended

2024-511917-40-00 Advanced Upper Gastrointestinal Tract Malignancies 2022-09-13
A phase II, open-label, single arm study to evaluate the efficacy of Luspatercept in Erythropoiesis-stimulating agent naive lower-risk MDS p… Ended

2024-516438-36-00 Patients with very low, low or intermediate risk myelod 2022-09-13
Binimetinib, Encorafenib and Pembrolizumab COmbination in MElanoma - Metastatic to the Brain Ended

2023-505302-42-00 BRAF(V600) mutation-positive melanoma with brain metast 2022-09-05
Phase II study to evaluate diarrhoea discontinuations at 3 cycles in patients with early-stage HER2 positive, hormone receptor positive brea… Ended

2024-514630-21-00 HER2 positive (HER2+), Hormone Receptor positive (HR+) 2022-08-11
A Study of an experimental drug, MK-2140 in combination with standard of care chemotherapy in participants with Diffuse Large B-Cell Lymphom… Ended

2022-501380-40-00 Diffuse large B-cell lymphoma (DLBCL) 2022-08-10
Pilot phase II study of Selinexor in combination with Ifosfamide, Etoposide and Dexamethasone (SIDE) in patients with relapsed or refractory… Ended

2024-513295-18-00 Relapsed or Refractory Peripheral T-cell Lymphomas 2022-08-10
Taletrectinib in ROS1 Positive Lung Cancer Phase 2 Global Study Ended

2024-516604-41-00 Non-small Cell Lung Cancer 2022-08-08
A Study of Sacituzumab Govitecan (IMMU-132) in Subjects with Metastatic Solid Tumors Ended

2024-513611-28-00 Metastatic Solid Tumors 2022-07-29
A phase II, monocentric, single arm trial evaluating the efficacy and safety of Pembrolizumab in combination with Lenvatinib in metastatic U… Ended

2024-514657-30-00 Metastatic uveal melanoma 2022-07-07
A Randomised, Open-Label, Phase 2 Study of Ceralasertib Monotherapy and Ceralasertib plus Durvalumab in Patients with Unresectable or Advanc… Ended

2024-512378-91-00 Unresectable or Advanced Melanoma 2022-06-24
Clinical trial to evaluate the effects of chemotherapy with anthracycline, after radiotherapy, in a group of pediatric and young adult patie… Ended

2024-519135-41-00 Glioblastoma 2022-06-21