Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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Trial aimed at examinate the functionality and effectiveness of the drug "IO" in adult patients with a rare form of cancer that affect the c… Recruiting

2023-510516-39-00 Acute B-cell Lymphoblastic Leukemia with minimal residu 2019-10-30
Palbociclib plus fulvestrant in women with hormone receptor positive and human epidermal growth factor receptor type 2 negative locally adva… Recruiting

2024-513372-18-00 Pre- and post-menopausal women with HR+/HER2- LABC or M 2019-10-18
SGM-LARRC: Multicenter, open-label, controlled, parallel arms clinical study on the performance of SGM-101, a fluorochrome-labeled anti-carc… Recruiting

2024-510768-21-00 Rectal cancer 2019-10-16
Phase 2a Study of Luspatercept in Pediatric Participants With Beta (β)-Thalassemia Recruiting

2022-502499-22-00 Beta (β) Thalassemia 2019-10-15
Neoadjuvant treatment in rectal cancer with radiotherapy followed by atezolizumab and bevacizumab Recruiting

2024-517119-59-00 Rectal cancer 2019-09-26
Cabozantinib plus Durvalumab in patients with advanced and chemotherapy-treated bladder carcinoma, of urothelial and non-urothelial histolog… Recruiting

2023-509821-29-00 bladder carcinoma of urothelial and non-urothelial hist 2019-09-25
Clinical utility of a next generation sequencing-based “oncochip” for therapeutic decision in metastatic breast cancer. Study SHARP Recruiting

2024-513934-40-00 Metastatic breast cancer 2019-09-20
Pre-operative phase II trial for breast cancer with nivolumab in combination with novel IO (BELLINI trial) Recruiting

2024-515080-54-00 Breast cancer 2019-08-15
Bacille Calmette-Guérin (BCG) vaccine in Radiologically Isolated Syndrome (RIS) Recruiting

2024-518901-16-00 RIS (Radiologically Isolated Syndrome) 2019-07-29
First-line Chemotherapy With Temozolomide Alone for Non-enhancing Adult Brainstem Gliomas, With a Diffuse Subtype and Showing Clinical and/o… Recruiting

2024-511862-35-00 Adults with non-contrast-enhancing diffuse brainstem gl 2019-07-19
CETUXIMAB, IRINOTECAN AND FLUOROURACILE IN FIRST-LINE TREATMENT OF IMMUNOLOGICALLY-SELECTED ADVANCED COLORECTAL CANCER PATIENTS - the CIFRA … Recruiting

2024-518987-11-00 ADCC 2019-06-12
Stereotactic Cisternal Lavage Therapy in Patients with Aneurysmal Subarachnoid Hemorrhage with Urokinase and Nimodipine for the Prevention o… Recruiting

2024-517798-25-00 Aneurysmal Subarachnoid Hemorrhage (aSAH) 2019-05-17
A Phase II Open-Label Study of Sacituzumab Govitecan in Unresectable Locally Advanced/Metastatic Urothelial Cancer Recruiting

2023-508302-24-00 Locally Advanced/Metastatic Urothelial Cancer 2019-05-07
The effect of androgen deprivation therapy on the expression of prostate specific membrane antigen (PSMA) in treatment naive metastatic pros… Recruiting

2024-519516-14-01 Metastatic prostate cancer, Prostate cancer 2019-04-15
A phase Ib/II randomized double-blind placebo controlled trial evaluating the effect of nivolumab for patients with in-transit melanoma meta… Recruiting

2023-509265-21-00 In-transit metastasis of malignant melanoma 2019-04-08
Atezolizumab After Chemo-radiotherapy for muscle-invasive bladder cancer Patients Not Eligible for Radical Cystectomy Recruiting

2024-512002-26-00 Muscle-invasive bladder cancer 2019-02-19
Allogeneic hematopoietic cell transplantation from HLA-matched donor after Flu-Mel-PTCy versus Flu-Mel-ATG reduced-intensity conditioning: a… Recruiting

2024-518568-11-00 Hematological malignancies confirmed histologically: - 2019-02-04
Trial that evaluates the interest of interruption versus maintaining the treatment of aromatase inhibitors in patients with metastatic low g… Recruiting

2024-512629-97-00 Patients with locally advanced or metastatic low grade 2019-01-23
Vitamin D Supplementation to increase free testosteron in Type 2 Diabetes Mellitus men: a Placebo-controlled Randomized Clinical Trial Recruiting

2024-514834-19-00 Type 2 Diabetes Mellitus 2018-12-05
A phase II study of Pembrolizumab plus Carboplatin in BRCA-related metastatic breast cancer Recruiting

2024-515686-34-00 BRCA-related metastatic breast cancer 2018-11-16
Randomised trial evaluating mifamurtide in combination with standard chemotherapy in patients with high-grade osteosarcoma at high risk of r… Recruiting

2024-514780-26-00 Patients ≤50 years old with high-risk osteosarcoma (def 2018-10-23
Treating severe brain-injured patients with apomorphine Recruiting

2023-504631-40-01 Disorder of Consciousness, severe brain injury 2018-09-05
A Repeated Dose-finding Study of Sarilumab in Children and Adolescents with Systemic Juvenile Idiopathic Arthritis (sJIA) Recruiting

2024-512701-11-00 Systemic Juvenile Idiopathic Arthritis (sJIA) 2018-08-29
Efficacy of immunotherapy in melanoma patients with brain metastases treated with steroids. The MEMBRAINS trial Recruiting

2024-516585-11-00 Advanced melanoma 2018-06-12