Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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Positron emission tomography with macrophage targeting to select individuals at risk for rheumatoid arthritis. Recruiting

2024-513538-40-02 ACPA positive arthralgia 2024-12-09
MITO 35a: a multicenter, prospective, single arm trial of Olaparib maintenance therapy in newly diagnosed BRCA wild-type advanced ovarian, … Recruiting

2024-516839-27-00 BRCA wild-type advanced ovarian, fallopian tube and pri 2024-12-09
[177Lu]Lu-PSMAI&T radioligand therapy (PSMA-RLT) for patients with prostate cancer and biochemical but not radio-morphological local recurre… Recruiting

2024-519348-34-00 prostate carcinoma 2024-12-09
A single-arm phase II study of cetuximab plus platinum and taxane-based chemotherapy followed by AVElumab and Cetuximab as first-line therap… Recruiting

2024-512053-24-00 recurrent/metastatic (R/M) head and neck squamous cell 2024-12-05
Randomized, double-blind, placebo-controlled trial of the efficacy and safety of tianeptine in the treatment of covid fog symptoms in patien… Recruiting

2024-510790-19-00 Covid fog - a dysfunctional condition characterized by 2024-12-02
A study to test long-term treatment with brigimadlin in people with solid tumours who took part in a previous study with this medicine Recruiting

2024-514177-21-00 Solid tumours 2024-12-02
Tau PET imaging in cognitively normal elderly subjects: A twin approach Recruiting

2024-517634-17-01 Healthy controls (investigating preclinical Alzheimer's 2024-12-02
Prospective phase IIb study to evaluate the efficacy of laparoscopic electrochemotherapy in the treatment of locally advanced pancreatic can… Recruiting

2024-519067-17-00 Locally Advanced Pancreatic Cancer 2024-12-02
Evaluation of the addition of Everolimus to 177Lu-DOTATATE in the treatment of grades 2 and 3 refractory meningioma: a phase IIb clinical tr… Recruiting

2023-508400-38-00 meningioma 2024-11-29
A multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 2 trial to evaluate the efficacy and safety of BP1.7881 in… Recruiting

2023-508949-40-00 Eosinophilic esophagitis 2024-11-29
Amyloid pathology in cognitively normal elderly subjects (PreclinAD) Recruiting

2024-518559-41-01 Healthy controls (investigating preclinical Alzheimer's 2024-11-29
An open-label study to evaluate the safety and tolerability of inhaled Teicoplanin in the treatment of Staphylococcus aureus (including mrsa… Recruiting

2024-517820-21-00 cystic fibrosis associated to persistent Staphylococcus 2024-11-29
A Phase II Study with Sevuparin in Subjects with Chronic Kidney Disease Recruiting

2024-513864-24-00 Chronic kidney disease 2024-11-28
Iberdomide combined with low-dose cyclophosphamide and dexamethasone: ICON study Recruiting

2023-508902-66-00 relapsed / refractory multiple myeloma 2024-11-28
A Phase 2, open label, randomized study of neoadjuvant dostarlimab plus CAPEOX versus CAPEOX in participants with previously untreated T4N0 … Recruiting

2024-513441-36-00 MMRp/ MSS colon cancer 2024-11-27
[18F]PEG-folate PET-CT imaging for monitoring of therapy response in Rheumatoid Arthritis patients Recruiting

2024-513537-21-02 Rheumatoid Arthritis 2024-11-27
Evolution of the initial distribution volume of glucose in the severe burned adults Recruiting

2024-513874-23-00 Severe burns 2024-11-27
LAG3 PET; ImmunoPET imaging with 89Zr-DFO-REGN3767 in patients with advanced solid cancer prior to and during treatment with cemiplimab with… Recruiting

2024-516795-15-00 Metastatic solid tumors, these may include but are not 2024-11-27
Carboplatin + Paclitaxel + Cetuximab (PCC) after failure of first line Immune checkpoint inhibitor with or without chemotherapy in recurrent… Recruiting

2024-512297-96-01 Head and neck squamous cell carcinoma 2024-11-26
Imaging of inflamed arteries in giant cell arteritis and inflamed joints in rheumatoid arthritis with a PET/CT scan. Recruiting

2024-514489-38-01 giant cell arteritis 2024-11-26
LAMAinDiab - comparison of 2 pharmacological therapies (lisdexamphetamine vs methylphenidate) for pediatric patients with ADHD and type 1 di… Recruiting

2023-506862-30-00 Attention-deficit hyperactivity disorder 2024-11-24
A Pilot, Randomized, Double-Blinded, Controlled Study of Hemodynamic and Acid Base Effects of 0.5M Sodium Lactate and 3% Saline Solutions in… Recruiting

2024-517927-37-00 Patients suffering from septic shock who require fluid 2024-11-24
Contribution of PET/CT with Gallium 68 citrate (68Ga-PET/CT) for the diagnosis of prosthetic valve infective endocarditis - CiGal-EI-TEP Recruiting

2024-514331-24-00 Prosthetic valve infective endocarditis 2024-11-22
Metronomic neoadjuvant capecitabine and cyclophosphamide in huge (PCI>28) Pseudomyxoma peritonei (PMP) patients candidates to cytoreductive … Recruiting

2024-514329-42-00 Pseudomyxoma peritonei patients with high tumor burden. 2024-11-22