Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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A Phase 2, Placebo-Controlled, Randomized, Double-Blind Study of 2 Doses of Crofelemer for the Treatment of adult patients with Short Bowel … Recruiting

2024-511994-31-00 Short Bowel Syndrome and Intestinal Failure (SBS-IF) wi 2025-03-10
MEtformin as a MEtabolic iNTervention in Oesophageal adenocarcinomas to improve response to neoadjuvant chemoradiotherapy Recruiting

2024-511626-30-00 Oesophageal adenocarcinoma 2025-03-09
Capecitabine plus pembrolizumab in patients with triple negative breast cancer after chemoimmunotherapy and surgery Recruiting

2023-505291-30-01 Triple Negative Breast Cancer with residual disease aft 2025-03-06
A prospective randomized single blind multicenter phase II study of organ perfusion with Custodiol-N compared with Custodiol in heart transp… Recruiting

2023-510492-57-00 heart transplantation in children 2025-03-05
Portal hypertension in cirrhosis Recruiting

2023-508535-32-00 Portal hypertension (PHT) and consequences in complicat 2025-03-04
Whole body HER3 quantification with radiolabelled Patritumab deruxtecan (HER3-DXd) PET/CT Recruiting

2023-508233-14-00 EGFR mutation positive advanced stage NSCLC 2025-03-03
KEYMAKER U01 Sub-Study E Signal-finding study to test investigational agents with pembrolizumab in combination with chemotherapy in newly di… Recruiting

2023-509234-19-00 Participants With Newly Diagnosed Resectable Stages II- 2025-03-03
Local Antibiotic Delivery for Community Acquired Pneumonia - Pilot study (LANDCAP1) Recruiting

2024-511413-37-00 Community-acquired pneumonia 2025-03-03
A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Atacicept Recruiting

2024-516380-81-00 Treatment of IgAN 2025-02-28
A study to learn more about how well treatment with sevabertinib (BAY2927088) tablets works and how safe it is in participants who have a so… Recruiting

2024-517419-62-00 HER2 mutation 2025-02-28
Long-term Extension Study for Participants with Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) in JNJ-81201887 … Recruiting

2022-500747-21-00 Geographic Atrophy 2025-02-27
The OxyTUTION Trial Recruiting

2024-516813-19-00 central diabetes insipidus 2025-02-26
Phase II study of Roginolisib in UM patients Recruiting

2024-514333-37-00 Advanced Metastatic Ocular/Uveal Melanoma 2025-02-25
A Pilot / Phase 2 Clinical Trial of GSL-01-001 Administered Orally for 12 Weeks Preceded by a 2 Week Screening Period in Patients Presenting… Recruiting

2024-514685-39-00 Irritable Bowel Syndrome (IBS) type D 2025-02-25
Phase II study to test whether a combination of three drugs—atezolizumab, vinorelbine, and weekly cyclophosphamide—can activate T-cells in p… Recruiting

2024-514031-20-00 Inoperable locally advanced or metastatic TNBC patients 2025-02-24
STROKE-POC Recruiting

2024-510866-18-00 Spasticity after Stroke 2025-02-21
Phase 2 Trial to determine the safety and efficacy of simultaneous treatment with ruxolitinib and extracorporeal photopheresis for patients … Recruiting

2023-507754-33-00 steroid-refractory chronic Graft-versus-Host-Disease 2025-02-19
Hypertonic lactate after cardiac arrest Recruiting

2023-506031-15-01 post-anoxic brain injury 2025-02-18
Open-label study of Asciminib for CML-CP or CML-AP patients with T315I mutation who are resistant, intolerant or ineligible to ponatinib Recruiting

2024-516049-38-00 CML-CP or CML-AP patients with T315I mutation 2025-02-18
Impact of CHOlinergic Stimulation on COgnitive and MOtor Functions and Brain Activity in Elderly Volunteers (CHOCOMO) - a randomised, placeb… Recruiting

2024-512172-35-00 neurological disorders 2025-02-17
A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients with Operable No… Recruiting

2023-509806-31-00 Non-Small Cell Lung Cancer 2025-02-11
Vericiguat in Vasospastic Angina (ViVA) Recruiting

2022-502998-42-00 Unequivocal epicardial and/or microvascular vasospastic 2025-02-10
Preparation for bone marrow transplantation through the combined use of chemo and radiotherapy (Reduced intensity: with lower doses or diffe… Recruiting

2024-514483-11-00 High-Risk Myelodisplastic Syndrome OR Acute Myeloid Leu 2025-02-10
Preparation for bone marrow transplant through the combined use of chemo and radiotherapy (intensive or myeloablative: eliminates stem cells… Recruiting

2024-514484-25-00 High-Risk Myelodisplastic Syndrome or Acute Myeloid Leu 2025-02-10