Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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[68Ga]Ga-FAPI PET/CT for response evaluation during immune checkpoint inhibitor therapy in malignant melanoma Recruiting

2023-509549-11-00 Malignant melanoma 2025-08-03
Encapsulated Fecal Microbiota Transfer to Treat Immune Activation in Patients with Cirrhosis and Ascites (TransImmune) – A randomized, doubl… Recruiting

2023-507790-18-00 cirrhosis and ascites 2025-08-01
Phase 2 Study of ZN‑c3 in High-Grade Serous Ovarian Cancer Recruiting

2022-502983-19-00 High-Grade Serous Ovarian, Fallopian Tube, or Primary P 2025-07-31
Detection of tumour DNA in the blood of patients receiving standard therapy for hormone receptor-positive (HR+) HER2 low expression (HER2 lo… Recruiting

2024-515349-41-00 Metastatic Breast Cancer HR+, HER2- 2025-07-29
Dapagliflozin in the treatment of decompensated liver cirrhosis: phase IIb randomised, controlled clinical trial Recruiting

2024-511964-95-00 Decompensated liver cirrhosis 2025-07-28
A Phase 2 Multicenter, Randomized, Platform Study of Targeted Therapies for the Treatment of Adult Subjects with Active Psoriatic Arthritis Recruiting

2024-519291-11-00 Psoriatic Arthritis 2025-07-25
Early intervention in plaque psoriasis: is bimekizumab able to delay chronic inflammation? Prospective multicenter interventional study Recruiting

2024-514647-29-01 psoriasis 2025-07-22
NEoadjuvant Chemotherapy and Immunotherapy for a selected group of inoperable pleural Mesothelioma patients (NECIM): a feasibility study Recruiting

2023-504302-11-02 inoperable pleural mesothelioma 2025-07-22
A study to learn about the safety and effectiveness of CRN04894 on participants Recruiting

2024-514846-35-00 CONGENITAL ADRENAL HYPERPLASIA 2025-07-22
A study to assess the efficacy and safety of ITI-1284 as monotherapy treatment in patients with Generalized Anxiety Disorder Recruiting

2024-516684-82-00 Generalized Anxiety Disorder 2025-07-21
A multicentre, randomised, double-blind, placebo-controlled, parallel-group trial to evaluate the efficacy and safety of BP1.4979 in adult p… Recruiting

2024-517987-46-00 Essential tremor 2025-07-21
A double-blind, randomized, controlled trial on the effect of PEX010 for prolonged grief disorder Recruiting

2024-518218-24-00 Prolonged grief disorder 2025-07-17
Randomized phase II trial of Cemiplimab plus OSE2101 (TEDOPI®) as maintenance therapy in ctDNA positive NSCLC. Recruiting

2024-519262-42-00 NSCLC non-small cell lung cancer 2025-07-15
Fecal Microbiota Transfer in Liver Cancer to Overcome Resistance to Atezolizumab/Bevacizumab – A randomized, placebo-controlled, double-blin… Recruiting

2023-506887-15-00 Hepatocellular carcinoma 2025-07-14
Evaluation of p-glycoprotein alterations in treatment-resistant depression: a [18F]MC225 PET study Recruiting

2023-508303-20-01 depression 2025-07-14
A study to assess the efficacy and safety of ITI-1284 in the treatment of Psychosis Associated with Alzheimer's Disease Recruiting

2024-513035-25-00 Psychosis associated with Alzheimer’s Disease 2025-07-11
Effectiveness of a Nerve Block in the Back of the Head for Treating Headaches Caused by Bleeding in the Brain Recruiting

2025-520619-15-00 headache pain related to SAH 2025-07-11
Sacituzumab govitecan (SG) with bevacizumab for the treatment of brain metastases from non-small cell lung cancer (NSCLC) Recruiting

2024-514066-40-00 Patients with metastatic non-squamous NSCLC pre-treated 2025-07-10
A Study to Assess the Adverse Events and Change in Disease Activity of Multiple Treatment Combinations with Telisotuzumab Adizutecan in Part… Recruiting

2024-512981-33-00 Metastatic Colorectal Cancer 2025-07-09
Evaluation of efficacy and safety of Cemiplimab as first line treatment for advanced basal cell carcinoma (CEMI-first) - An open label, sing… Recruiting

2024-517647-31-00 basal cell carcinoma 2025-07-09
Neoadjuvant chemo-immunotherapy for stage III PD-L1 positive Non-Small Cell Lung Cancer (NSCLC) Recruiting

2024-519205-35-01 stage III PD-L1 positive Non-Small Cell Lung Cancer (NS 2025-07-08
An Open-Label Extension Study of Subjects who Received an Avalyn Inhaled Antifibrotic Agent Recruiting

2024-518289-28-00 Progressive pulmonary fibrosis [PPF] Idiopathic pulmon 2025-07-04
Treatment with acetylcholine esterase inhibitors in anorexia nervosa : a multicenter double-blind randomised controlled trial versus placebo Recruiting

2024-511681-37-00 Anorexia nervosa 2025-07-02
Study of the treatment of patients with non-small cell lung cancer with metastasis with Cemiplimab and subsequent treatment with Cemiplimab … Recruiting

2024-518812-38-00 Non-small cell lung cancer (NSCLC) 2025-07-02