Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis Recruiting

2025-520721-21-00 Rheumatoid Arthritis 2025-10-20
the EMPOWER Study Recruiting

2023-508610-42-00 Hyponatremia 2025-10-17
A Study to Evaluate the Long-term Safety and Effectiveness of APG777 in Subjects with Atopic Dermatitis Recruiting

2024-519795-11-00 Atopic Dermatitis 2025-10-06
Clinical trial to evaluate the efficacy and safety of pirtobrutinib in combination with rituximab in patients with indolent clinical forms o… Recruiting

2024-511983-97-00 Adult patients with indolent MCL who have not previousl 2025-09-29
A study to investigate efficacy and safety of brivekimig in participants with Crohn’s disease Recruiting

2024-517016-30-00 Crohn’s disease 2025-09-26
Treatment of osteoarthritis behind the kneecap with tissue engineered nasal cartilage in a randomized, controlled, multicenter clinical tria… Recruiting

2023-508640-21-00 Patellofemoral osteoarthritis 2025-09-22
A Phase 2 Randomized Trial Evaluating Efficacy of AGA2118 in Postmenopausal Women with Low Bone Mass (ARTEMIS) Recruiting

2024-515610-41-00 Postmenopausal Osteoporosis 2025-09-11
A Randomized, Parallel-Group, Double-Blind, Placebo-Controlled, Monotherapy Study of the Efficacy, Safety, and Tolerability of SPT-300 in Ad… Recruiting

2025-521240-37-00 Major Depressive Disorder (MDD), with or without Anxiou 2025-09-11
Osimertinib plus chemotherapy as 1st line therapy in stage IV NSCLC patients with atypical EGFR mutations (AIO-TRK/YMO-0324) Recruiting

2024-516790-78-00 stage IV NSCLC (non-small-cell lung cancer) 2025-09-04
A Phase 2a Study of the Safety and Efficacy of OD-07656 and of Subsequent Vedolizumab Therapy in Moderately to Severely Active Ulcerative Co… Recruiting

2024-520201-39-00 Moderately to Severely Active Ulcerative Colitis 2025-08-28
A clinical study of treatments for non-small cell lung cancer (MK-3475-01I) Recruiting

2024-518839-11-00 Stage IV Squamous Non-Small Cell Lung Cancer 2025-08-25
A Phase 2a, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics o… Recruiting

2024-520202-19-00 Subjects with Intestinal Failure-Associated Liver Disea 2025-08-19
A study to test if difelikefalin is safe in adolescents with itching related to long term kidney disease Recruiting

2023-509909-74-00 Pruritus 2025-08-13
ImmunotherApy for the Prevention of High-Risk Oral DIsorders malignanT transformation - APHRODITE trial Recruiting

2025-521490-13-00 Oral disorders 2025-07-30
A study to determine how safe MB-CART2019.1 is and how well it works in children and adolescents with B cell neoplasms Recruiting

2023-506348-17-00 Relapsed/refractory (r/r) mature B cell neoplasms who h 2025-07-22
Neoadjuvant Tebentafusp in Patients with Metastatic Uveal Melanoma Recruiting

2023-509076-42-00 Metastatic uveal melanoma with resectable liver metasta 2025-07-18
A phase 2 placebo-controlled trial to investigate visugromab in combination with immunochemotherapy (ICT) in first-line treatment of partici… Recruiting

2024-516792-32-01 Metastatic non-squamous non-small cell lung cancer 2025-07-18
A PHASE 2 STUDY TO RESEARCH THE SAFETY AND EFFICACY OF TRASTUZUMAB DERUXTECAN VERSUS CDK4/6I PLUS ENDOCRINE THERAPY IN ADVANCED BREAST CANCE… Recruiting

2024-512360-55-00 Unresectable locally recurrent or metastatic hormone re 2025-06-30
Phase 2, Multicenter, Open label, Platform Study investigating Tarlatamab (AMG 757) in patients with Metastatic/Locally Advanced Small-Cell … Recruiting

2024-515847-47-00 Metastaic small cell lung cancer (SCLC) and other poorl 2025-06-24
SerCaBot-2302 - Serratus Plane Block (SPB) versus Capsaicin versus Botulinum toxin type A for the chronic neuropathic pain of post-mastectom… Recruiting

2024-517420-20-00 Chronic neuropathic pain of post-mastectomy syndrome 2025-06-10
A phase 2, double-masked, randomized, multicenter, parallel group, placebo-controlled study to investigate the efficacy and safety of GAL-10… Recruiting

2024-519128-26-00 Non-foveal geographic atrophy secondary to non-neovascu 2025-05-22
Exploring the mechanistic link between the oxytocinergic system and mindfulness training Recruiting

2024-513482-39-00 Psychological distress complaints 2025-05-15
A Study to see How Well and How Safely Different Treatments Work in a Group of Patients with Non-Small Cell Lung Cancer, Chosen Based on the… Recruiting

2024-511239-91-00 Resectable Stage I-III Non-Small Cell Lung Cancer (NSCL 2025-05-05
A study to evaluate the safety, tolerability, and pharmacokinetics of VABOMERE (meropenem-vaborbactam) in children with complicated urinary … Recruiting

2024-516360-29-00 Complicated Urinary Tract Infection (cUTI), Acute Pyel 2025-04-25