Phase I – First Administration to Humans

807 trials 323 recruiting

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A Phase 1 study to look at RP-6306 in combination with FOLFIRI as a treatment for Advanced Solid Tumours Ended

2024-511927-32-00 Advanced solid tumours
An Open-Label, Multicenter, Phase 1 Study Evaluating the Safety and Pharmacokinetics of ADU-1604 in Adults with Advanced Melanoma Ended

2024-511949-19-00 Metastatic Melanoma
Study to Evaluate Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-291 Moves Through the Body in Adult Partici… Ended

2024-512586-13-00 Non-Hodgkin's Lymphoma
A Phase 1a/1b Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of BGB-5… Ended

2024-514704-13-00 Advanced or Metastatic Solid Tumors with KRAS Mutations
INTERACT stomach Ended

2024-516265-37-00 Stomach Cancer with metastasis in the peritoneum
FIRST-IN-HUMAN OPEN-LABEL MULTICENTRE CLINICAL TRIAL TO EVALUATE THE SAFETY AND EFFICACY OF EPICARDIAL IMPLANTATION OF COLLAGEN MEMBRANES WI… Ended

2024-517738-16-00 ventricular failure caused by ischemic heart disease
First-in-human (FIH) Study of DS-1471a in Subjects with Advanced Solid Tumors Ended

2024-517984-21-00 Advanced Solid Tumors
C6081001: A Phase 1 Study of PF-07985045 in Participants with Advanced Solid Tumors Ended

2024-517988-23-00 KRAS mutated advanced solid tumors
MESENCHYMAL STROMAL CELL THERAPY FOR THE TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME - Validation of Mechanistic Pathways and Clinical … Ended

2024-518160-13-00 Acute Respiratory Distress Syndrome - ARDS
A phase 1, controlled, open-label, single dose, dose-escalation, clinical proof-of-concept study of MRI enhanced with ADx-001 (DSPE-DOTA-Gd … Ended

2024-520078-36-00 Alzheimer's disease
A Study of EOS006215 in Adult Participants with Advanced Solid Tumors Ended

2024-520369-30-00 Solid Tumors
SPECT/CT imaging of FPI-2505 in patients with solid tumours; a phase 0 molecular imaging basket trial (SCOPE-study). Ended

2025-521235-37-00 small cell lung cancer, non-smallcell lung cancer, colo
A Phase 1/1b Open-Label Dose-Escalation and Dose-Optimization Study of Bcl-2 Inhibitor BGB 21447 in Patients With Mature B Cell Malignancies Ended

2025-521600-21-00 mature B-Cell malignancies
A trial to find out how well CVHNLC works at different dose levels and how safe it is in combination with pembrolizumab in patients with lun… Ended

2024-519651-28-00 metastatic squamous non-small cell lung cancer
A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of KD033 (SAR445710) in Subjects With Metast… Ended

2022-503080-15-00 Cancer