Phase I/II – Other

643 trials 280 recruiting

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Phase I/IIa multicentre study of infusion of autologous peripheral blood T lymphocytes expanded and genetically modified using Sleeping Beau… Recruiting

2024-514544-90-00 Relapsed or refractory B-cell lymphoma 2024-03-11
A Phase 1/2, Open-Label, Randomized, Dose Finding and Dose Expansion Study of Gedatolisib in Combination with Darolutamide in Metastatic Cas… Recruiting

2023-505898-32-00 Metastasic Castration-Resistant Prostate Cancer (mCRPC) 2024-02-28
A study in men with advanced prostate cancer to determine the safety and effects of a test drug (Lutetium (177Lu) rhPSMA 10.1 injection) Recruiting

2024-511537-35-00 Metastatic castration-resistant prostate cancer (mCRPC) 2024-02-09
Allogeneic CARCIK-CD19 in adults/pediatric B-cell Non Hodgkin Lymphoma or Chronic Lymphocytic Leukemia Recruiting

2023-505511-20-00 B-Non Hodgkin Lymphoma and Chronic Lymphocytic Leukemia 2024-01-29
Clinical Trial with Adipose Tissue Stem Cells on Biological Matrix for the Treatment of Venous Ulcer of the Lower Limbs. Recruiting

2024-513151-33-00 Venous ulcer of the lower limbs 2024-01-19
Neoadjuvant trastuzumab, pertuzumab and tucatinib without chemotherapy in HER2-positive breast cancer: the TRAIN-4 study Recruiting

2024-518192-61-00 Breast cancer 2023-12-08
International proof of concept therapeutic Stratification trial of Molecular Anomalies in Relapsed or Refractory HEMatological malignancies … Recruiting

2022-501869-41-00 Acute Lymphoblastic Leukemia, in Relapse Lymphoblastic 2023-11-14
A study to examine the safety, tolerablity, body distribution and efficacy of [90Y]Y-PentixaTher therapy in CNS lymphoma patients. Recruiting

2024-512097-98-00 Central nervous system (CNS) lymphoma; recurrent or ref 2023-11-07
Phase 1/2 Study of Oral Nuvisertib (TP-3654) in Patients with Myelofibrosis Recruiting

2022-502597-16-00 Intermediate or High-risk Primary or Secondary Myelofib 2023-10-27
Clofarabine Therapy in Patients with Locally Advanced or Metastatic Urothelial Carcinoma: a Phase 1/2 Dose-Escalation Study Recruiting

2024-516586-37-00 Urothelial carcinoma 2023-10-24
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons with Severe or Moderate … Recruiting

2023-503906-35-00 Severe or Moderate Hemophilia A with or without factor 2023-10-11
Assessment of the effect of Wharton's jelly mesenchymal stem cell preparation (WJMSCs) in the treatment of fibrotic interstitial lung diseas… Recruiting

2024-514433-38-00 fibrotic interstitial lung disease 2023-09-28
Can a single dose of psilocybin reduce alcohol intake in patients with alcohol use disorder? Recruiting

2024-517497-17-01 Alcohol Use Disorder 2023-09-01
A Prospective Phase I/II, Single-Arm, Open-Label, Multicentre Study to Evaluate the Safety and Efficacy of Tafasitamab (MOR00208) in Pediatr… Recruiting

2024-511336-28-00 Leukemia in childhood 2023-08-11
A study to evaluate the safety and efficacy of the tumor-targeting human antibody-cytokine fusion protein L19TNF plus lomustine in patients … Recruiting

2022-501822-39-00 Glioblastoma 2023-07-31
Combination treatment of Belantamab Mafodotin and Venetoclax in treatment of relapsed and refractory t(11;14) Multiple Myeloma (Phase I/IIa)… Recruiting

2024-511794-30-00 Multiple Myeloma 2023-06-28
A study to look at how safe divarasib is when given on its own or in combination with other anti-cancer therapies, and how well these medici… Recruiting

2023-507171-22-00 Untreated Advanced or Metastatic Non-Small Cell Lung Ca 2023-06-21
Trial evaluating the safety and efficacy of Venetoclax in addition to a standard conditioning regime in patients with certain forms of leuke… Recruiting

2024-514688-24-00 Patients with myelodysplastic syndrome (MDS), chronic m 2023-05-26
Phase I/II Study of inducible HLAG+ Regulatory T Cells (iG-Tregs) in patients undergoing HLA-matched sibling donor allogeneic haematopoietic… Recruiting

2024-520084-14-00 Adopt immunotherapy in adult patients undergoing hemato 2023-05-26
A Study of Debio 0123 in Combination with Temozolomide in Adult Participants with Recurrent or Progressive Glioblastoma and of Debio 0123 in… Recruiting

2022-502156-31-00 Glioblastoma 2023-05-26
This study has 2 phases: a Phase 1b evaluation of elacestrant in combination with abemaciclib followed by a Phase 2 evaluation of elacestran… Recruiting

2024-512878-98-00 Brain Metastasis from Estrogen Receptor Positive, HER-2 2023-05-16
CAR-T cells in systemic B cell mediated autoimmune disease - CASTLE Recruiting

2024-516819-24-00 Systemic Sclerosis 2023-05-16
Platform study of JDQ443 in combinations in patients with advanced solid tumors harboring the KRAS G12C mutation Recruiting

2023-506716-41-00 Adult patients with advanced (metastatic or unresectabl 2023-05-08
Study to evaluate the ability of a sublingual vaccine to induce the expression of trained immunity in peripheral blood cells Recruiting

2024-516720-34-00 Healthy adult males and non-pregnant females 2023-03-31