Topotecan Hydrochloride

4 trials

Filter these 4 trials by condition, phase, country and more.

Open in Search →

4 Registered trials

0 Recruiting

2 Completed trials

4 Sponsors

15 Countries

Phase III

Phase I/II

Phase III: 3 Phase I/II: 1

Oversight events:

1 unexpected event across 1 trial

View oversight register →

Indications tested

Ovarian cancer 2 Fallopian tube cancer 1 Small cell lung cancer 1 Neuroblastoma 1 Medulloblastoma 1 Rhabdomyosarcoma 1 Glioblastoma 1 Peritoneal cancer index 1

Sponsors using this IMP

Incyte Corp. 1 Mural Oncology Inc. 1 Novartis Pharma AG 1 Zai Lab (US) LLC 1

All trials

4 total

Phase 3 Study of INCB123667 Versus Investigator's Choice of Chemotherapy in Platinum Resistant Ovarian Cancer With Cyclin E1 Overexpression Pending

2025-522748-42-00 Phase III 8 countries Incyte Corp.
A Study to Test How Well ZL-1310 may Work Compared to Therapies Selected by the Investigator in Treating Patients with Relapsed Small Cell L… Pending

2025-522818-23-00 Phase III 11 countries Zai Lab (US) LLC
Study to assess safety and identify dose of ribociclib in combination of temozolomide and topotecan (TOTEM) in patients (12 months – 21 year… Ended

2024-512095-35-00 Phase I/II 7 countries Novartis Pharma AG
Study of Nemvaleukin Alfa in Combination with Pembrolizumab Versus Investigator's Choice Chemotherapy in Patients with Platinum-Resistant Ep… Ended

2024-513230-38-00 Phase III 10 countries Mural Oncology Inc.

Showing 1–4 of 4 trials

← All drugs A–Z