Methotrexate Disodium — Drug Intelligence | 10 EU Trials

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10 Registered trials

3 Recruiting

6 Completed trials

10 Sponsors

8 Countries

Phase III

Phase II/III

Phase IV

Phase III: 6 Phase II/III: 1 Phase IV: 3

Oversight events:

1 serious breach across 1 trial

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Indications tested

Hypophosphatasia 1 Rheumatoid arthritis 1 Psoriatic arthropathy 1 Peripheral spondyloarthritis 1

Sponsors using this IMP

Alexion Pharmaceuticals Inc. 1 Fundacion Para La Investigacion Biomedica Del Hospital Clinico San Carlos 1 Klinikum Der Landeshauptstadt Stuttgart gKAöR 1 Medical Center - University Of Freiburg 1 Medical University Of Lodz 1 Medical University Of Silesia Katowice Poland 1 Sint Maartenskliniek Stichting 1 Universitaetsklinikum Heidelberg AöR 1 Universitair Medisch Centrum Utrecht 1 Universitair Ziekenhuis Gent 1

All trials

10 total

Discontinuation of disease-modifying anti-rheumatic drugs (DMARDs) in rheumatoid arthritis patients also using TNF inhibitors Pending

2026-525316-33-00 Phase IV 1 country Sint Maartenskliniek Stichting
Single-arm interventional study with ruxolitinib and AIEOP-BFM 2017 Poland or AIEOP-BFM 2017 standard of care chemotherapy in children with … Recruiting

2024-518316-39-00 Phase II/III 1 country Medical University Of Lodz
Age-adjusted high-dose chemotherapy followed by autologous stem cell transplantation or conventional chemotherapy with R-MP as first-line tr… Recruiting

2024-512320-11-00 Phase III 2 countries Medical Center - University Of Freiburg
An unblinded clinical Trial with random assignment to Treatment Groups in adult patients with psoriatic arthrits to evaluate how far immunos… Recruiting

2023-508251-39-00 Phase III 2 countries Universitaetsklinikum Erlangen AöR
AIEOP-BFM 2017 POLAND - Collaborative treatment protocol for children and adolescents with acute lymphoblastic leukemia - A randomized phas… Ended

2024-517253-27-00 Phase III 1 country Medical University Of Silesia Katowice Poland
Optimizing MATRix, a combination of Methotrexate, Ara-C, Thiotepa and Rituximab given as an induction therapy, de-escalated in duration and … Ended

2024-514473-21-00 Phase III 3 countries Klinikum Der Landeshauptstadt Stuttgart gKAöR
SPondyloArthritis: inducing drug-free Remission by early TNF-Alpha bloCkade Under guidance of Single cell RNA sequencing and epigenetic prof… Ended

2023-510085-27-00 Phase III 1 country Universitair Ziekenhuis Gent
CO-THEIA (COMBINATION THERAPY WITH METHOTREXATE AND ADALIMUMAB FOR UVEITIS): EFFICACY, SAFETY AND COST-EFFECTIVENESS OF METHOTREXATE, ADALIM… Ended

2024-513123-17-00 Phase III 1 country Fundacion Para La Investigacion Biomedica Del Hospital Clinico San Carlos
STRENSIQ® Immunogenicity Study Ended

2022-502793-17-00 Phase IV 1 country Alexion Pharmaceuticals Inc.
TOFA-PREDICT Ended

2024-510903-12-00 Phase IV 1 country Universitair Medisch Centrum Utrecht

Showing 1–10 of 10 trials

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