Lidocaine Hydrochloride — Drug Intelligence | 26 EU Trials

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26 Registered trials

11 Recruiting

6 Completed trials

22 Sponsors

10 Countries

Phase III

Phase II

Phase IV

Phase III: 6 Phase II: 6 Phase III/IV: 1 Phase IV: 12 Phase I (Other): 1

Oversight events:

1 serious breach 3 temporary halts across 3 trials

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Indications tested

Sickle cell disease 2 Sickle cell anaemia with crisis 1 Cardiac valve disease 1 Hydrocele 1 Sickle cell anaemia 1 Hepatectomy 1 Spermatocele 1 Head and neck cancer 1 Perioperative analgesia 1 Coronary artery disease 1 Obesity 1

Sponsors using this IMP

Centre Hospitalier Universitaire De Nantes 5 Region Midtjylland 2 Centre Hospitalier Universitaire Amiens Picardie 1 Centre Hospitalier Universitaire Grenoble Alpes 1 CHU Saint Pierre 1 Clinica Universidad De Navarra 1 Consorci Sanitari Integral 1 Fundacio De Recerca Clinic Barcelona-Institut D’Investigacions Biomediques August Pi I Sunyer 1 Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau 1 Fundacion Para El Fomento De La Investigacion Sanitaria Y Biomedica De La Comunitat Valenciana 1 Hospital San Pedro 1 Hospital Universitario La Paz 1

All trials

26 total

SERRATUS : Evaluation of the Analgesia by Serratus Plane Block During Pleural Drainage in Intensive Care Unit. Pending

2024-515722-83-00 Phase III 1 country Centre Hospitalier Universitaire Amiens Picardie
Lidocaine for opioid sparing in vaso-occlusive crisis of Sickle Cell Disease Pending

2024-518437-28-00 Phase III 1 country Centre Hospitalier Universitaire De Nantes
LOCAL INVASIVE TREATMENT OF TRAPEZIUS MUSCLE PAIN IN PATIENTS WITH FIBROMYALGIA Pending

2024-520345-23-00 Phase IV 1 country Fundacio De Recerca Clinic Barcelona-Institut D’Investigacions Biomediques Augus…
LASER volunteer trial: Local Anaesthetic Systemic Effect during Regional anaesthesia procedures Pending

2025-520910-67-01 Phase IV 1 country Oslo University Hospital HF
Prevenir el dolor en las primeras 24-48h después de una cirugía de la mama. Se aplica inyectando con jeringa a nivel local, un anestésico ll… Pending

2025-521162-10-00 Phase IV 1 country Consorci Sanitari Integral
ILHEP : Effect of perioperative Intravenous Lidocaine on postoperative opioid related-side effects after open HEPatectomy: a multicentre pro… Pending

2025-522462-73-00 Phase IV 1 country Centre Hospitalier Universitaire De Rennes
Morphine PCA vs Morphine and Lidocaine PCA for the treatment of vaso-occlusive crisis-related pain in sickle-cell anaemia patients: a prospe… Pending

2025-523777-41-01 Phase IV 1 country CHU Saint Pierre
Pilot study comparing the efficacy of intra-articular glenohumeral injection combined with suprascapular nerve block versus intra-articular … Pending

2026-525317-31-00 Phase II 1 country Centre Hospitalier Universitaire De Nantes
A randomized, open-label, Phase III trial to assess the efficacy and safety of BupiZenge compared to lidocaine for pain associated with oral… Recruiting

2025-524386-24-00 Phase III 4 countries OncoZenge AB
Randomized and controlled clinical trial of the efficacy and safety of the use of lidocaine and magnesium sulfate for lung resection surgery… Recruiting

2023-509503-33-00 Phase IV 1 country Clinica Universidad De Navarra
Evaluation of the effect of intravenous lidocaine on the systemic inflammatory response associated with cardiopulmonary bypass in patients u… Recruiting

2025-523534-11-00 Phase II 1 country Hospital San Pedro
Effectiveness of a Nerve Block in the Back of the Head for Treating Headaches Caused by Bleeding in the Brain Recruiting

2025-520619-15-00 Phase II 1 country Fundacio Institut De Recerca De L'Hospital De La Santa Creu I Sant Pau
Evaluation of the efficacy of sphenopalatine block in headache in patients with non-traumatic subarachnoid hemorrhage (SAH) after training o… Recruiting

2024-514282-19-00 Phase II 1 country Centre Hospitalier Universitaire Grenoble Alpes
Sclerotherapy of hydro and spermatoceles with 2ml Aetoxysclerol 30mg/ml vs. a combination of 2ml Aetoxysclerol 30mg/ml and 25ml of ethanol 9… Recruiting

2022-502284-38-00 Phase III 1 country Region Jamtland Harjedalen
Betamethasone meniscal infiltration under ultrasound control: a randomized, double-blind, placebo-controlled multicenter trial. Recruiting

2023-510079-74-00 Phase III 1 country Centre Hospitalier Universitaire De Toulouse
MESOTHERAPY IN LATERAL EPICONDYLITIS, A RANDOMIZED, DOUBLE- BLIND STUDY TO COMPARE THE EFFICACY OF MESOTHERAPY WITH PIROXICAM AND LIDOCAINE … Recruiting

2024-519158-34-00 Phase II 1 country Instituto De Medicina Molecular Joao Lobo Antunes; Unidade Local De Saude De San…
General anesthesia versus sedation with high-flow nasal cannula for the endovascular treatment of acute ischemic stroke Recruiting

2024-510752-12-00 Phase IV 1 country Hospital Universitario La Paz
Comparison of local anaesthesia and regional anaesthesia (PECS II block) on QoR-15 in patients undergoing subpectoral implantation of cardia… Recruiting

2023-508997-27-00 Phase IV 1 country Medizinische Universitaet Innsbruck
A randomized clinical trial to compare topical lidocaine-prilocaine cream (Emla) versus 2% lidocaine infiltration to first-degree perineal t… Recruiting

2024-512728-12-00 Phase IV 1 country Fundacion Para El Fomento De La Investigacion Sanitaria Y Biomedica De La Comuni…
ElderLIDO_1 : Pharmacokinetic study of intravenous lidocaine in young and elderly patients Ended

2024-513932-11-00 Phase IV 1 country Centre Hospitalier Universitaire De Rennes
Opioid-Free General Anesthesia Compared to Opioid-Based General Anesthesia for the Reduction of Postoperative Nausea and Vomiting in Patient… Halted

2025-521047-20-00 Phase IV 1 country Institut De Recerca Biomedica De Lleida Fundacio Dr. Pifarre
Comparison of cocaine, lidocaine/xylometazoline and saline for intranasal analgesia - A blinded triple crossover study Ended

2023-506644-17-01 Phase III 1 country Rigshospitalet
Duration of peripheral nerve blocks in opioid tolerant individuals Ended

2023-509351-13-00 Phase IV 1 country Region Midtjylland
The effect of the Popliteal Plexus Block on muscle function of the leg - a scientific trial in healthy volunteers Ended

2023-505263-37-00 Phase III/IV 1 country Region Midtjylland

Showing 1–24 of 26 trials

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