Clinical Trials in Italy — Country Dashboard | 3,681 EU Studies

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3,681 Registered trials

1,489 Recruiting

1,842 Completed trials

891 Sponsors active

775 Research sites

Phase III

Phase II

Phase III: 1645 Phase II/III: 152 Phase II: 1113 Phase I/II: 212 Phase III/IV: 28 Phase IV: 153 Phase I: 119 Phase I (Other): 111 Phase I (FiH): 142 Other: 5 Other: 1

Oversight events in trials active here:

107 serious breaches 827 temporary halts 64 urgent safety measures 84 unexpected events 162 corrective measures across 455 trials

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Top conditions

Non-small cell lung cancer 135 Non-small cell lung cancer metastatic 50 Ovarian cancer 32 Diffuse large B-cell lymphoma 27 Breast cancer 27 Crohn's disease 26 Colorectal cancer 26 Endometrial cancer 25 Prostate cancer metastatic 23 Systemic lupus erythematosus 22 Myasthenia gravis 21 Asthma 20

Top sponsors

Merck Sharp & Dohme LLC 180 AstraZeneca AB 161 Novartis Pharma AG 145 F. Hoffmann-La Roche AG 138 Janssen - Cilag International 93 AbbVie Deutschland GmbH & Co. KG 88 Sanofi-Aventis Recherche & Developpement 75 Bristol-Myers Squibb Services Unlimited Company 64 Pfizer Inc. 63 Amgen Inc. 60 Glaxosmithkline Research & Development Limited 60 Boehringer Ingelheim International GmbH 49

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3,681 total

Dose-ranging study evaluating the efficacy and safety of EVO756 in adults with Chronic Spontaneous Urticaria. Pending

2024-518786-10-01 Phase II Moderate to Severe Chronic Spontaneous Urticaria Evommune Inc.
Dose Range Finding, Efficacy, and Safety Study of Nebulized CSL787 in Adults with Non-cystic Fibrosis Bronchiectasis (NCFB) Pending

2024-518821-13-00 Phase II Non-cystic Fibrosis Bronchiectasis CSL Behring LLC
Phase 2, open-label, multicentre, single-arm study to evaluate the activity of the combination of EGFR inhibitors and c-MET inhibitors in pa… Pending

2024-518892-72-00 Phase II Head and neck cancer Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia
Phase II Prospective Multicenter Study of High-Dose Treosulfan/Melphalan as Consolidation Treatment in Newly Diagnosed High-Risk and Very Hi… Pending

2024-518912-37-01 Phase II Ewing Sarcoma Fondazione Santobono Pausilipon Onlus
Use of pegfilgrastim in severe chronic neutropenia Pending

2024-519009-36-01 Phase II Severe chronic neutropenia (SCN) IRCCS Istituto Giannina Gaslini
A Multicentre, Randomised Phase Ib Trial to evaluate Neoadjuvant Immunotherapy Combination of Nivolumab alone or plus Ipilimumab with the IL… Pending

2024-519010-31-00 Phase I (Other) High-Risk, Surgically Resectable Melanoma Fondazione Melanoma Onlus
DETECTION RATE AND CLASSIFICATION OF BREAST LESIONS WITH DIGITAL MAMMOGRAPHY WITH CONTRAST MEDIUM (CEDM) ALONE AND IN COMBINATION WITH TOMOS… Pending

2024-519017-62-00 Phase II breast pathology IRCCS Istituto Nazionale Tumori Fondazione Pascale
A randomized phase III trial of short-course versus long-course pre-operative chemotherapy with mFOLFIRINOX or PAXG regimen for stage I-III … Pending

2024-519031-42-00 Phase III pancreatic ductal adenocarcinoma Associazione Italiana Per Lo Studio Del Pancreas
ORGAN SPARING FOR LOCALLY ADVANCED RECTAL CANCER AFTER NEOADJUVANT TREATMENT FOLLOWED BY ELECTROCHEMOTHERAPY - LARC_ DEEP_CANCERS Pending

2024-519050-37-00 Phase II colorectal cancer IRCCS Istituto Nazionale Tumori Fondazione Pascale
Phase II, open label, single arm, multicenter study to assess the activity and safety of ALectinib as NE O adjuvant therapy in patients with… Pending

2024-519106-12-00 Phase II Patients with anaplastic lymphoma kinase positive (ALK+) loc… G.O.I.R.C. Gruppo Oncologico Italiano Di Ricerca Clinica
HeArt Rate and quality of Life in transthyrEtin cardiac amYloidosis (HARLEY) Pending

2024-519107-10-00 Phase IV transthyretin cardiac amyloidosis Universita' Degli Studi Di Genova
Receptor radionuclide therapy with 177Lu-DOTATOC (177Lu- edotreotide or 177Lu-octreotide) in SSTR positive patients: a multicenter, prospect… Pending

2024-519183-40-00 Phase II NET Istituto Romagnolo Per Lo Studio Dei Tumori Dino Amadori IRST S.r.l.
Phase 2A–Evaluation of AUP1602-C with foam dressing as a new treatment for diabetic foot ulcers Pending

2024-519317-66-00 Phase II Diabetic Foot Ulcer Aurealis Oy
A multicentre, prospective, open-label, non-comparative study to evaluate menstrual bleeding typology, tolerability, and compliance during a… Pending

2024-519403-10-00 Phase IV Female contraception. Italfarmaco S.p.A.
NEurotrophins Mimetic compound for the treatment of diabetic foot UlcerS Pending

2024-519405-35-00 Phase I (FiH) Diabetic Foot Ulcer Mimetech S.r.l.
VINORELBINE INHIBITS ONCOGENIC FUNCTIONS OF MKK3: A NEW THERAPEUTIC OPPORTUNITY FOR PATIENTS WITH METASTATIC COLORECTAL CANCER Pending

2024-519459-27-00 Phase II METASTATIC COLORECTAL CANCER I.F.O. Istituti Fisioterapici Ospitalieri
A Study to Compare Linvoseltamab Monotherapy and Linvoseltamab + Carfilzomib Combination Therapy with Standard-of-Care Combination Regimens … Pending

2024-519504-27-00 Phase III Relapsed Refractory Multiple Myeloma Regeneron Pharmaceuticals Inc.
A Phase II, Randomized, Trial of Niraparib Versus Best Supportive Careas Maintenance Treatment In Patients With Locally Advanced Or Metastat… Pending

2024-519519-32-00 Phase II urothelial cancer Universita' Degli Studi Di Torino
Cannabis extrAct in oncology Patients for the treatment of TUmor Related symptom burden (CAPTURE) Pending

2024-519568-42-00 Phase II Patients with advanced oncologic disease receiving active tr… IRCCS Istituto Nazionale Tumori Fondazione Pascale
A clinical trial to learn about the long-term safety of FUB523 (zigakibart) in people with immunoglobulin A (IgA) nephropathy who have compl… Pending

2024-519638-22-00 Phase III IgA nephropathy Novartis Pharma AG
Exploratory study to evaluate the safety and tolerability of tamoxifen citrate in the treatment of cystic fibrosis in patients without mutat… Pending

2024-519657-11-00 Phase II cystic fibrosis Azienda Ospedaliera Universitaria Integrata Verona
Deflazacort TREATment in LMNArelated Pending

2024-519672-12-00 Phase II Laminopathies Azienda Ospedaliero Universitaria Pisana
A Study to Evaluate how Pozelimab + Cemdisiran Combination Therapy Works in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) wh… Pending

2024-519709-37-00 Phase III Paroxysmal nocturnal hemoglobinuria (PNH) Regeneron Pharmaceuticals Inc.
A Phase Ib/II Open-Label, Multicentre Platform Study Evaluating Novel Combinations in Participants with Advanced or Metastatic Non-Small Cel… Pending

2024-519786-22-01 Phase I/II metastatic non-small cell lung cancer (NSCLC) AstraZeneca AB

Showing 145–168 of 3,681 trials

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